Food Science and Human Wellness Open Access Editor-in-Chief: Bin Cong
Home Food Science and Human Wellness All Issues Volume 15 Issue 8
Volume 15 Issue 8, August 2026
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The Application of Typical Natural Compounds in the Fields of Human Health and Nutrition
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31 articles
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Review | Open Access
The potential of flavonoids as microbiota-directed foods regulating lipid metabolism via the gut-liver axis
Yijiang Wei, Jing Luo, Lianchao Zhang, [...], Liru Zhang, Xinhong Huang, Yiwei Chai, Wenjing Wang, Qingqing Yan, Yingying Qiu, Baokun Li, Zhexin Fan, Zhifeng Fang << Fewer
Published: 01 September 2026
2026, 15(8): 9250599
Review | Open Access
Hydroxycinnamic acids in chicory: implications for gut health and ulcerative colitis mitigation
Ruiqi Huang, Xi Chen, Junjie Chen, [...], Runhe Zhang, Yang Yang, Ye Peng, Quancai Sun << Fewer
Published: 19 August 2026
2026, 15(8): 9250617
Review | Open Access
From waste to wellness: dietary fiber and polyphenol synergies from plant-based food by-products in gut health and precision nutrition
Lin Ji, Ziheng Yang, Wei Wang, [...], Wenhui Qi, Chunyu Kang, Jilu Sun, Xianghong Wang, Liwen Wang << Fewer
Published: 19 August 2026
2026, 15(8): 9250981
Original Article | Open Access
Rosmarinic acid, the key dietary antioxidant in Rosmarinus officinalis L. identified by integrated screening, targets PPARγ to activate Nrf2/NQO1 axis and mitigate oxidative stress
Zhenhua Liang, Haiyang Liang, Wenfeng Shi, [...], Dongqi Liu, Yinfei Sun, Zhenhua Liu, Wenyi Kang << Fewer
Published: 19 August 2026
2026, 15(8): 9251121
Original Article | Open Access
Identification of chemical compositions in ethnic Cinnamomum chago kernels based on UPLC-MS/MS analysis and their potential antioxidant and cytoprotective activities
Zhenzhen Liang, Tianhao Li, Bodou Zhang, [...], Sheng Li, Jinglin Li, Haiying Wu, Wenyi Kang, Yu Zhang << Fewer
Published: 19 August 2026
2026, 15(8): 9250625
Original Article | Open Access
Coix seed seedlings-derived exosome-like nanovesicles as a natural, stable and highly effective nanoscale radioprotective agent for alleviating ionizing radiation-induced damage
Xue Li, Yongqi Liu, Zhangning Qiao, [...], Beijie Li, Yanling Shi, Juanjuan Yi, Jike Lu << Fewer
Published: 01 September 2026
2026, 15(8): 9250791
Original Article | Open Access
Protective effects and potential mechanism of Cyclocarya paliurus (Batal.) Iljinskaja flavonoids on DSS-induced colitis in mice
Huihui Xiong, Hui Chen, Lingli Chen, [...], Kehui Ouyang, Qingfeng Zhang, Suyun Lin, Wenjun Wang << Fewer
Published: 19 August 2026
2026, 15(8): 9250653
Original Article | Open Access
Application of multi-omics to reveal the protective mechanism of Portulaca oleracea ethanol extract against alcoholic liver disease in mice
Shumei Wu, Fen Liu, Weiming Hu, Qi Zhang
Published: 01 September 2026
2026, 15(8): 9250597
Original Article | Open Access
Integrated microbiome and metabolomic analysis uncover the amelioration mechanisms of Prunella vulgaris L. polysaccharides on gut health of ulcerative colitis
Ziyin Li, Wei Li, Feifei Xu, [...], Yuefei Lai, Xinxin Yin, Xiaoxuan Xiao, Xinhui Xing, Xingfen Yang << Fewer
Published: 01 September 2026
2026, 15(8): 9250652
Original Article | Open Access
Docosahexaenoic acid-acylated astaxanthin esters alleviate cisplatin-induced acute kidney injury by modulating the ferroptosis-related GPX4/xCT signaling pathway and reducing oxidative stress
Youyan Wang, Lipin Chen, Haohao Shi, [...], Jierui Zhao, Penglin Xiang, Zhongyuan Liu, Guanghua Xia, Yuming Wang << Fewer
Published: 01 September 2026
2026, 15(8): 9250647
Original Article | Open Access
Screening, stability, and in vitro hypolipidemic activity of pancreatic lipase inhibitory peptides from walnut dregs
Tingting Li, Jing Xie, Zishan Hong, [...], Li Zhang, Jingjing Dai, Yuying Bai, Jun Sheng, Yang Tian << Fewer
Published: 01 September 2026
2026, 15(8): 9250600
Original Article | Open Access
Leucine metabolite β-hydroxy-β-methyl-butyrate alleviates cisplatin-induced peripheral neuropathy by destabilizing CTR1 in dorsal root ganglia
Shilong Ning, Yuzhuo Gong, Xiao Ma, [...], Yang Lou, Huixian Jin, Xianguo Chen << Fewer
Published: 01 September 2026
2026, 15(8): 9250602
Original Article | Open Access
Formononetin mitigates neuroinflammation-induced depressive-like behaviors via metabolic remodeling of the gut microbiota
Wenzhi Hao, Lu Wang, Yalin Li, [...], Yingren Zhang, Weidong Pan, Xiang Luo, Xiaoxu Zhu, Yali Huang, Nanbo Wang, Li Yan, Junqing Huang, Jiaxu Chen << Fewer
Published: 01 September 2026
2026, 15(8): 9250552
Original Article | Open Access
Plant sterol ester of α-linolenic acid alleviates hepatic steatosis associated with improving lysosomal function and promoting autophagy via inhibiting mTORC1
Hao Han, Yanyang Han, Tingli Xue, [...], Yajing Dong, Shuqi Ji, Mingming Zheng << Fewer
Published: 01 September 2026
2026, 15(8): 9250601
Original Article | Open Access
Multi-omics reveal mechanisms of Lachnospiraceae bacterium mediated intestinal protective effect of paeoniflorin in diarrhea-predominant irritable bowel syndrome
Yuanyuan Wei, Chao Han, Yimeng Fan, [...], Sijuan Huang, Zhuo Chen, Jianyu Lü, Zhihui Hao << Fewer
Published: 01 September 2026
2026, 15(8): 9250555
Original Article | Open Access
Astragali Radix prevents hypertension in SHRs via suppressing inflammation and modulating serum metabolism: integrated in vivo pharmacological validation, network pharmacology, molecular docking, and metabolomics
Yue Yang, Ju Chen, Saifei Zhu, [...], Rui Gao, Yuehua Zhang, Hongye Zhang, Jianru Dong, Mengyu Liu, Xin Zhong, Weifan Yao, Minjie Wei, Weiwei Tong, Mingyan Liu << Fewer
Published: 01 September 2026
2026, 15(8): 9250559
Original Article | Open Access
Mechanisms of apigenin in mitigating APAP-induced hepatocyte pyroptosis and liver injury via TRPV4 activation and ESCRT-mediated membrane repair
Zhuoqun Meng, Shuang Guan, Ranran Zhang, [...], Chunyun Wang, Xuming Deng, Jing Lu << Fewer
Published: 01 September 2026
2026, 15(8): 9250554
Original Article | Open Access
Revealing the lactation-promoting mechanism of the phenolic extracts in Hemerocallis citrina Baroni based on network pharmacology, transcriptomics, proteomics, and molecular docking
Jiaxu Chen, Zhaoping Pan, Qili Li, [...], Yanyang Wu, Shuangshuang Ma, Xinyi Zhang, Jiahao Xiao, Xiaopeng Li, Jiajing Guo, Tao Li, Fuhua Fu, Yang Shan << Fewer
Published: 01 September 2026
2026, 15(8): 9250557
Original Article | Open Access
Anti-tumor immune effect of ginseng glucosyl oleanolate transformed from ginsenoside Ro by activating the cGAS/STING pathway and regulating gut microbiota in cervical cancer
Sitong Liu, Guangquan Ren, Yongzhe Liu, [...], Zhiyi Ai, Hongyang Zou, Xia Li, Yu Wang, Bo Nan, Yuhua Wang << Fewer
Published: 01 September 2026
2026, 15(8): 9250631
Original Article | Open Access
Study on the effect of quercetagetin on reducing uric acid through cell and animal research
Mei Li, Shuyu Liu, Si Mi, [...], Liwen Wang, Yunhe Lian, Yaxin Sang, Xianghong Wang << Fewer
Published: 01 September 2026
2026, 15(8): 9250657
Original Article | Open Access
Myricitrin induces browning of white adipose tissue in mice via the ERα pathway
Guangning Kou, Yuting Huang, Shuhao Fang, [...], Amin Ullah, Erni Guo, Sha Zhang << Fewer
Published: 01 September 2026
2026, 15(8): 9250656
Original Article | Open Access
Bangia fusco-purpurea polysaccharide exerts immunomodulatory effects through Lactobacillus murinus-mediated macrophage polarization via the MAPK/NF-κB-IL10 signaling axis
Jingna Wu, Nan Pan, Xiaoting Chen, [...], Zhiyu Liu, Xiaoya Qu << Fewer
Published: 01 September 2026
2026, 15(8): 9250603
Original Article | Open Access
Uncovering the detoxifying power of Glycyrrhizae Radix et Rhizoma: a breakthrough in combating Psoraleae Fructus-induced liver injury by suppressing NLRP3 inflammasome activation
Yingjie Xu, Longxin Guo, Jincai Wen, [...], Wen Kan, Caiping He, Zhanjiang Hu, Ping Zhang, Yuming Guo, Xiaoyan Zhan, Xiaohe Xiao, Zhaofang Bai << Fewer
Published: 01 September 2026
2026, 15(8): 9250655
Original Article | Open Access
Ginseng glucosyl oleanolate inhibited ATP production and induced ferroptosis in non-small cell lung cancer
Yue Hu, Guangquan Ren, Xinzhu Wang, [...], Zhiyi Ai, Sitong Liu, Jing Ge, Yidan Luo, Yu Wang, Bo Nan, Xia Li, Yuhua Wang << Fewer
Published: 01 September 2026
2026, 15(8): 9250632
Original Article | Open Access
Anti-obesity effects of narirutin and hesperidin in immature Citrus reticulata extract via AMPK activation in high-fat diet-fed mice
Sou Hyun Kim, Doyoung Kwon, Chawon Yun, [...], Joung-Hee Kim, Kyung-Mi Kim, Gi Yeon Bae, Min Hye Yang, Yun-Hee Lee, Young-Suk Jung << Fewer
Published: 01 September 2026
2026, 15(8): 9250649
Original Article | Open Access
Imperatae Rhizoma extract alleviates atopic dermatitis through regulating PI3K/AKT/NF-κB signaling pathway and Staphylococcus aureus
Shuo Zhang, Yifan Zhang, Yuwan He, [...], Shujie Cheng, Hongliang Qian, Chongjiang Cao, Qiaoyan Yue, Dejun Hu << Fewer
Published: 01 September 2026
2026, 15(8): 9250556
Original Article | Open Access
Chrysin alleviate obesity in mice by regulating gut microbiota and TLR4/JNK signaling pathway
Yanzhe Cheng, Haoran Qiu, Xuanyi Liu, [...], Zhisheng Wang, Yaning Chang, Yingjun Zhou << Fewer
Published: 01 September 2026
2026, 15(8): 9250598
Original Article | Open Access
L-Theanine alleviates heat stress via modulating the transcriptional regulation of Hsph1 by Hsf1
Ling Lin, Yi Xiang, Zhihua Gong, [...], Qinyu Zhou, Xi Xiang, Shumin Han, Wenjun Xiao << Fewer
Published: 01 September 2026
2026, 15(8): 9250648
Original Article | Open Access
Study of screening in silico novel peptides from soy protein and deciphering their binding behavior and interaction mechanism with α-glucosidase
Yue Xu, Yang Yang, Chunmin Ma, [...], Xiaofei Liu, Yan Wang, Bing Wang, Xin Bian, Guang Zhang, Yinyuan He, Na Zhang << Fewer
Published: 01 September 2026
2026, 15(8): 9250650
Original Article | Open Access
Transcriptome analysis of cerebral organoids reveals the potential of walnut oil unsaponifiable matter to benefits neural development and cognition
Junjun Zhou, Dan Hong, Liang Yue, [...], Jiaxin Song, Siting Li, Zhimin Yun, Yingxia Tan, Aijin Ma << Fewer
Published: 01 September 2026
2026, 15(8): 9250630
Original Article | Open Access
Atractylodes macrocephala polysaccharides 1 ameliorate ulcerative colitis by regulating gut microbiota and IL-17RA signaling pathway
Mingjiang Mao, Qingling Meng, Chenhuan Shentu, [...], Shijie Dai, Na Zhu, Chengxin Hu, Yangsheng Wu, Xiaofeng Yuan << Fewer
Published: 01 September 2026
2026, 15(8): 9250651