Latest Issue - SciOpen

Open Access

Overview on signal transduction cascades regulation roles of garlic and its bioactive constituents

Ammad Ahmad Farooqi, Iqra Mobeen, Rukset Attar, [...], Khalida I. Noel, Baojun Xu, William C. Cho << Fewer

Published: 10 October 2024

2024, 13(5): 2353-2362

Open Access

Antiglycating effects of citrus flavonoids and associated mechanisms

Yunli Xiao, Junfeng Shen, Jianfeng Zhan, [...], Limin Guo, Chi-Tang Ho, Shiming Li << Fewer

Published: 10 October 2024

2024, 13(5): 2363-2372

Open Access

Application and prospects of proteomic technology in inflammation: a review

Senye Wang, Yanhai Chu, Jiajia Yuan, [...], Yiqi Li, Zhenhua Liu, Xiaoyu Chen, Wenyi Kang << Fewer

Published: 10 October 2024

2024, 13(5): 2373-2385

Open Access

Impact of phytoconstituents on oral health practices: a post COVID-19 observation

Harsh Kumar, Reena Singh, Daljeet Singh Dhanjal, [...], Chirag Chopra, Natália Cruz-Martins, Gheyath K. Nasrallah, Amin F. Majdalawieh, Sivakumar Manickam, Shahida Anusha Siddiqui, Dinesh Kumar, Indu Sharma, Varun Sharma << Fewer

Published: 10 October 2024

2024, 13(5): 2386-2400

Open Access

Nattokinase as a functional food ingredient: therapeutic applications and mechanisms in age-related diseases

Hao Wu, Qian Zhang, Hao Suo, [...], Feng Xu, Wanxu Huang, Dan Ohtan Wang << Fewer

Published: 10 October 2024

2024, 13(5): 2401-2409

Open Access

Insights into the enhancement of food flavor perception: strategies, mechanism and emulsion applications

Luyao Huang, Yujie Dai, Fan Zhang, [...], Longtao Zhang, Baodong Zheng, Yi Zhang << Fewer

Published: 10 October 2024

2024, 13(5): 2410-2424

Open Access

Lignans are the main active components of Schisandrae Chinensis Fructus for liver disease treatment: a review

Ke Fu, Shu Dai, Cheng Ma, [...], Yafang Zhang, Shenglin Zhang, Cheng Wang, Lihong Gong, Honglin Zhou, Yunxia Li << Fewer

Published: 10 October 2024

2024, 13(5): 2425-2444

Open Access

Molecular mechanisms of aflatoxin neurotoxicity and potential neuroprotective agents

Chongshan Dai, Erjie Tian, Hui Li, [...], Subhajit Das Gupta, Zhihui Hao, Zhanhui Wang, Tony Velkov, Jianzhong Shen << Fewer

Published: 10 October 2024

2024, 13(5): 2445-2455

Open Access

Health effects of fruit juices and beverages with varying degrees of processing

Xinyue Zhang, Xiaojun Liao, Yongtao Wang, [...], Lei Rao, Liang Zhao << Fewer

Published: 10 October 2024

2024, 13(5): 2456-2479

Open Access

Nutritional values, bioactive compounds and health benefits of purslane (Portulaca oleracea L.): a comprehensive review

Yanxi Li, Longgao Xiao, Huan Yan, [...], Mingyi Wu, Xiaojiang Hao, Haiyang Liu << Fewer

Published: 10 October 2024

2024, 13(5): 2480-2501

Open Access

Mechanisms and active substances of targeting lipid peroxidation in ferroptosis regulation

Hui Chen, Lingli Chen, Wenjun Wang

Published: 10 October 2024

2024, 13(5): 2502-2518

Open Access

New food sources and production systems: a comparison of international regulations and China’s advancements in novel foods with synthetic biology

Xin Liu, Di Wu, Yi Shao, Yongning Wu

Published: 10 October 2024

2024, 13(5): 2519-2542

Open Access

2’-Fucosyllactose alleviate immune checkpoint blockade-associated colitis by reshaping gut microbiota and activating AHR pathway

Shikai Yan, Leilei Yu, Fengwei Tian, [...], Jianxin Zhao, Wei Chen, Qixiao Zhai << Fewer

Published: 10 October 2024

2024, 13(5): 2543-2561

Open Access

Oral administration of egg white ovotransferrin prevents osteoporosis in ovariectomized rats

Nan Shang, Xiaoyu Bao, Michael Doschak, Jianping Wu

Published: 10 October 2024

2024, 13(5): 2562-2572

Open Access

DIA-based quantitative proteomic analysis on porcine meat quality at different chilling rates

Yuqiang Bai, Tongjing Yan, Fei Fang, [...], Xin Li, Su Wang, Juan Li, Chengli Hou, Dequan Zhang << Fewer

Published: 10 October 2024

2024, 13(5): 2573-2583

Open Access

Oxidative stress mediates glycidol-induced endothelial injury and its protection by 6-C-(E-2-fluorostyryl)naringenin

Yue Zhou, Hui Xu, Ka-Wing Cheng, [...], Feng Chen, Qian Zhou, Mingfu Wang << Fewer

Published: 10 October 2024

2024, 13(5): 2584-2594

Open Access

Facile SERS screening of melamine in bovine milk with 2D printed AgNPs/glass fabric filter paper as the flexible substrate

Shiyao Wang, Yanan Zhao, Xiao Wei, Yisheng Chen

Published: 10 October 2024

2024, 13(5): 2595-2600

Open Access

Dioscin from Polygonatum sibiricum induces apoptosis and autophagy in Ishikawa human endometrial cancer cell and in vivo

Xiaoli Li, Runhui Ma, Zhijing Ni, [...], Wei Wang, Kiran Thakur, Jianguo Zhang, Zhaojun Wei << Fewer

Published: 10 October 2024

2024, 13(5): 2601-2616

Open Access

Dietary polyphenols reduced the allergenicity of β-lactoglobulin via non-covalent interactions: a study on the structure-allergenicity relationship

Chi Zhang, Qiaozhi Zhang, Huatao Li, [...], Zhouzhou Cheng, Shiyu Fan, Hujun Xie, Zhongshan Gao, Yan Zhang, Linglin Fu << Fewer

Published: 10 October 2024

2024, 13(5): 2617-2628

Open Access

Curcumin delivery nanoparticles based on Maillard reaction of Haematococcus pluvialis protein/galactose for alleviating acute alcoholic liver damage

Xinyi Liu, Yukun Song, Shasha Cheng, Mingqian Tan

Published: 10 October 2024

2024, 13(5): 2629-2641

Open Access

Tetramethylpyrazine and paeoniflorin combination (TMP-PF) alleviates atherosclerosis progress by reducing hyperlipemia and inhibiting plaque angiogenesis via the NR4A1/VEGFR2 pathway

Rong Yuan, Qiqi Xin, Weili Shi, [...], Yu Miao, Zhengchuan Zhu, Yahui Yuan, Ying Chen, Xiaoning Chen, Sean Xiao Leng, Keji Chen, Weihong Cong << Fewer

Published: 10 October 2024

2024, 13(5): 2642-2652

Open Access

Quercetin inhibits truncated isoform of dopamine- and cAMP-regulated phosphoprotein as adjuvant treatment for trastuzumab therapy resistance in HER2-positive breast cancer

Han-Sheng Chang, Tzu-Chun Cheng, Shih-Hsin Tu, [...], Chih-Hsiung Wu, You-Cheng Liao, Jungshan Chang, Min-Hsiung Pan, Li-Ching Chen, Yuan-Soon Ho << Fewer

Published: 10 October 2024

2024, 13(5): 2653-2667

Open Access

Maternal dietary patterns associated with bone density in Chinese lactating women and infants at 6 months postpartum: a prospective study using data from 2018-2019

Yalin Zhou, Xiaoyu Zhu, Ying Lü, [...], Runlong Zhao, Hanxu Shi, Wanyun Ye, Zhang Wen, Rui Li, Hanming Huang, Yajun Xu << Fewer

Published: 10 October 2024

2024, 13(5): 2668-2676

Open Access

Anti-biofilm and anti-virulence potential of cell free supernatant of Akkermansia muciniphila against Salmonella

Jiaxiu Liu, Wenxiu Zhu, Huanhuan Liu, [...], Xiaomeng Ren, Ningbo Qin, Xiaodong Xia << Fewer

Published: 10 October 2024

2024, 13(5): 2677-2689

Open Access

Adjuvant postbiotic administration improves dental caries prognosis by restoring the oral microbiota

Qing Liu, Teng Ma, Cuijiao Feng, [...], Yalin Li, Hao Jin, Xuan Shi, Lai-Yu Kwok, Yan Shi, Tingtao Chen, Heping Zhang << Fewer

Published: 10 October 2024

2024, 13(5): 2690-2702

Open Access

Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway

Lan Li, Shengye Yang, Xinyu Liang, [...], Yameng Liu, Hualing Xu, Xiaozhen Guo, Cen Xie, Xiaojun Xu << Fewer

Published: 10 October 2024

2024, 13(5): 2703-2717

Open Access

The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro

Xue Li, Yiwen Shao, Limin Hao, [...], Qiaozhen Kang, Xiaolong Wang, Jiaqing Zhu, Changcheng Zhao, Yanling Shi, Jike Lu, Juanjuan Yi << Fewer

Published: 10 October 2024

2024, 13(5): 2718-2726

Open Access

Sulforaphane ameliorates non-alcoholic steatohepatitis by KLF4-mediated macrophage M2 polarization

Xianghui Huang, Jia Xu, Ye Xu, [...], Bingxin Huangfu, Feng Zhang, Yanzhou Hu, Ruxin Gao, Xinxin Ren, Boyang Zhang, Kunlun Huang, Xiaoyun He << Fewer

Published: 10 October 2024

2024, 13(5): 2727-2740

Open Access

Effects of axylitol-casein complex on insulin resistance and gut microbiota composition in high-fat-diet + streptozotocin-induced type 2 diabetes mellitus mice

Fanhua Kong, Juan Zhang, Shimo Kang, [...], Xinyu Shen, Aicheng Liu, Yan Zheng, Junhua Shao, Xiqing Yue << Fewer

Published: 10 October 2024

2024, 13(5): 2741-2753

Open Access

Structural characteristics of phenylboronic acid-modified astaxanthin ester and its effect on DSS-induced ulcerative colitis by blocking reactive oxygen species and maintaining intestinal homeostasis

Xing Qiao, Hongyan Li, Qun Gao, [...], Zhigao Wang, Jie Xu, Lu Yang, Changhu Xue << Fewer

Published: 10 October 2024

2024, 13(5): 2754-2764

Open Access

Microbiomics and metabolomics insights into the microbial regulation on the formation of flavor components in the traditional fermentation process of Chinese Hongqu aged vinegar

Shangong Tong, Wenlong Li, Yuandong Rao, [...], Yanqin Xiao, Yingyin Yan, Weiling Guo, Xucong Lü, Jinyuan Sun, Lianzhong Ai, Li Ni << Fewer

Published: 10 October 2024

2024, 13(5): 2765-2778

Open Access

High β-sitosterol-D-glucoside content in sweet potato varieties and its anti-breast cancer potential through multiple metastasis-associated signals

Jinyin Zhang, Lu Huang, Xiang Tang, [...], Miao Pan, Xiaoli Ye, Xuegang Li, Hang Ma << Fewer

Published: 10 October 2024

2024, 13(5): 2779-2789

Open Access

Effects of salt and rice flour concentration on microbial diversity and the quality of sour meat, a Chinese traditional meat

Mengyang Liu, Xinping Lin, Jing Yang, [...], Xu Yan, Chaofan Ji, Huipeng Liang, Sufang Zhang, Liang Dong << Fewer

Published: 10 October 2024

2024, 13(5): 2790-2798

Open Access

Amelioration of dextran sodium sulphate-induced colitis in mice by treatment with Lactobacillus rhamnosus and Lactobacillus reuteri: intraspecific and interspecific patterns

Chunxiu Lin, Yuxing Zheng, Bo Zhang, [...], Guopeng Lin, Kexin Shang, Jianxin Zhao, Gang Wang, Wei Chen << Fewer

Published: 10 October 2024

2024, 13(5): 2799-2812

Open Access

Fufang E’jiao Jiang’s effect on immunity, hematopoiesis, and angiogenesis via a systematic “compound-effect-target” analysis

Xiang Li, Xiao Xu, Ying Dong, [...], Shusheng Fan, Xueyang Ren, Yuan Zheng, Jiamu Ma, Feng Zhang, Qingyue Deng, Xianxian Li, Yingyu He, Mengyu Sun, Wei Liu, Mengxia Li, Qing Xia, Yan Zhang, Gaimei She << Fewer

Published: 10 October 2024

2024, 13(5): 2813-2832

Open Access

Lactobacillus from fermented bamboo shoots prevents inflammation in DSS-induced colitis mice via modulating gut microbiome and serum metabolites

Xiangru Liu, Xiaoling Lu, Hao Nie, [...], Jing Yan, Zhiwen Ma, Hailin Li, Shixin Tang, Qi Yin, Jingfu Qiu << Fewer

Published: 10 October 2024

2024, 13(5): 2833-2846

Open Access

Oligomeric procyanidins combined with Parabacteroides distasonis ameliorate high-fat diet-induced atherosclerosis by regulating lipid metabolism, inflammation reaction and bile acid metabolism in ApoE^-/- mice

Mingjuan Xu, Cheng Lü, Yiqing Hu, [...], Mo Zhang, Jinxin Shen, Chunyi Liu, Qun Lu, Rui Liu << Fewer

Published: 10 October 2024

2024, 13(5): 2847-2856

Open Access

Longitudinal investigation of mineral composition in human milk and its correlation with infant anthropometric outcomes among Tibetan mother-infant dyads during the first 6 months postpartum

Xiaomei Zhang, Yaling Wang, Junying Zhao, [...], Weicang Qiao, Yanpin Liu, Lijun Chen << Fewer

Published: 10 October 2024

2024, 13(5): 2857-2865

Open Access

Research on the quality deterioration of UHT milk products during shelf life: core microorganisms and related characteristics

Ruixue Ding, Kairu He, Rina Wu, [...], Mengxue Lou, Zhili Liu, Yuqiong Piao, Xiaoyan Liu, Zhishen Mu, Junrui Wu << Fewer

Published: 10 October 2024

2024, 13(5): 2866-2875

Open Access

Strain-specific effect of Streptococcus thermophilus consumption on host physiology

Peng Yu, Yang Jiang, Yuqi Pan, [...], Min Guo, Bo Yang, Xiaoming Liu, Jianxin Zhao, Hao Zhang, Wei Chen << Fewer

Published: 10 October 2024

2024, 13(5): 2876-2888

Open Access

Dietary L-proline supplementation ameliorates autism-like behaviors and modulates gut microbiota in the valproic acid-induced mouse model of autism spectrum disorder

Jingjing Fang, Ruixuan Geng, Seong-Gook Kang, [...], Kunlun Huang, Tao Tong << Fewer

Published: 10 October 2024

2024, 13(5): 2889-2905

Open Access

Improvement of glucose metabolism in middle-aged mice on a high-fat diet by whole-grain highland barley is related to low methionine levels

Chuanxing Feng, Yueting Ge, Bowen Li, [...], Xiangrong Cheng, Xue Tang, Jianjin Zhu, Yuge Jiang, Yonghui Shi, Guowei Le << Fewer

Published: 10 October 2024

2024, 13(5): 2906-2916

Open Access

Carbonic anhydrase 2 mediates anti-obesity effects of black tea as thermogenic activator

Peng Ma, Jie Xiao, Biyu Hou, [...], Ping He, Xinyu Yang, Yisa Wang, Zijing Wang, Tianshu Xu, Xiuying Yang, Xuan Zhu, Shasha Xiang, Song Li, Guanhua Du, Jian Ying, Guifen Qiang << Fewer

Published: 10 October 2024

2024, 13(5): 2917-2936

Open Access

Characterization of squash polysaccharide and the anti-diabetic effect on type 2 diabetic rat revealed by urine metabolomics analysis

Li Liang, Fuming Zhang, Quanhong Li, [...], Baoguo Sun, Yuyu Zhang, Robert J. Linhardt << Fewer

Published: 10 October 2024

2024, 13(5): 2937-2946

Open Access

Capsaicin alleviates the hepatic clock gene disruption and gut microbiota dysbiosis in circadian rhythm disorder mouse model

Bolin Lin, Chi-Tang Ho, Yawen Wang, [...], Jie Xiao, Muwen Lu << Fewer

Published: 10 October 2024

2024, 13(5): 2947-2958

Open Access

Maillard reaction affecting immunobinding activity and digestibility of tropomyosin in Alectryonella plicatula food matrix

Chenchen Yu, Xinrong He, Nairu Ji, [...], Shuai Kang, Dongxiao Li, Huilin Zhang, Yang Yang, Dong Lai, Qingmei Liu, Guangming Liu << Fewer

Published: 10 October 2024

2024, 13(5): 2959-2969

Open Access

Effect of exogenous free N^ε-(carboxymethyl)lysine on diabetes-associated cognitive dysfunction: neuroinflammation, and metabolic disorders

Huang Zhang, Lan Mo, Xi Chen, [...], Mei Li, Maiquan Li, Yang Xu, Maomao Zeng, Zhiyong He, Qingwu Shen, Jie Chen, Wei Quan << Fewer

Published: 10 October 2024

2024, 13(5): 2970-2981

Open Access

Ganoboninketal C from Ganoderma boninense improves the efficacy of CDDP-based chemotherapy through inhibiting translesion DNA synthesis

Xiaolu Ma, Fei Yang, Ke Ma, [...], Hongyan Shen, Junjie Han, Kai Wang, Yeran Yang, Jiawei Zhu, Ruiyuan An, Qilin Wang, Tie-Shan Tang, Bo Zhou, Hongwei Liu, Caixia Guo << Fewer

Published: 10 October 2024

2024, 13(5): 2982-2992

Open Access

Mitigation of polycyclic aromatic hydrocarbons (PAHs) in roasted beef patties by cold plasma treatment and products quality evaluation

Yuke Hou, Yangjian Hu, Min Li, [...], Jiahui Nong, Fengyuan Xie, Yuhan Fan, Jianhao Zhang, Xianming Zeng, Minyi Han, Xinglian Xu, Xia Wang << Fewer

Published: 10 October 2024

2024, 13(5): 2993-3005

Open Access

Comparative genomic analysis revealed that dietary habits affected the adaptation of Bifidobacterium bifidum to the intestinal tract in different geographic populations

Min Li, Jie Yu, Weicheng Li, [...], Qiong Wu, Jiaqi Sun, Zhihong Sun << Fewer

Published: 10 October 2024

2024, 13(5): 3006-3017