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Open Access Article Issue
An efficient fuzzy logic-integrated hybrid deep learning framework for medical diagnosis
Fuzzy Information and Engineering 2026, 18(1): 1-18
Published: 09 May 2026
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Medical diagnosis involves analyzing symptoms, test results, and patient histories, but uncertainty from vague symptoms and incomplete records complicates the process. Fuzzy logic-based systems address this issue but often depend on manual rule creation, which is time-consuming. This research proposes a hybrid approach integrating fuzzy logic with deep learning techniques (FL-DLT) for intelligent diagnosis. The framework combines adaptive neuro-fuzzy inference system (ANFIS) for handling uncertainty with convolutional neural networks (CNNs) for extracting features from medical images like X-rays and MRIs. ANFIS models relationships between symptoms, results, and diagnoses, while CNNs analyze medical images. Experimental results show high accuracy and reliability, even with noisy or incomplete data. The proposed approach can improve diagnostic accuracy and efficiency, supporting clinicians in decision-making. Key contributions include the development of the FL-DLT framework and its evaluation using a large dataset of patient records and medical images. Additionally, the research offers insights into the application of fuzzy logic and deep learning in medical diagnosis, highlighting their potential to enhance diagnostic outcomes and efficiency in clinical practice.

Open Access Article Issue
Fuzzy computational intelligence in personalized medicine and diagnosis
Fuzzy Information and Engineering 2025, 17(4): 472-483
Published: 12 December 2025
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Downloads:104

The development of fuzzy computational intelligence (FCI) has emerged as an effective method for personalized medicine and diagnosis. FCI effectively handles uncertainty and imprecision in medical data, facilitating patient-specific treatment recommendations. Conventional diagnostic and treatment methods typically rely on fixed threshold-based approaches, which fail to account for individual variations in patient responses, leading to suboptimal treatment outcomes. This study proposes the personalized treatment recommendation using fuzzy logic (PTR-FC) framework for diabetes (DB) patients to address these challenges. The framework integrates patient-specific data such as blood glucose levels, diet, exercise, and medication history into the fuzzy inference system (FIS), supporting personalized treatment recommendations. The treatment plans are dynamically adapted based on individual patient outcomes using linguistic factors and fuzzy rules (FR). The proposed method dynamically adjusts recommendations in real time, potentially enhancing personalized treatment and improving decision-making in DB management. Additionally, it promotes lifestyle modifications while reducing the risk of medication-induced complications. The effectiveness of the proposed method was compared to conventional methods, demonstrating improved treatment accuracy, increased patient adherence, and reduced adverse health risks. The PTR-FC framework offers a more adaptive and effective approach to DB management, ensuring better patient outcomes.

Open Access Article Issue
Harnessing fuzzy logic framework to quantify diagnostic uncertainty in medical decision support
Fuzzy Information and Engineering 2025, 17(4): 425-445
Published: 12 December 2025
Abstract PDF (9.7 MB) Collect
Downloads:104

Medical diagnosis has become increasingly difficult, requiring sophisticated systems to manage decision-making uncertainty. The proposed medical diagnosis utilizing fuzzy logic framework (MD-FLF) addresses medical data imprecision and ambiguity by employing fuzzy inference techniques. Clinical data ambiguity is often overlooked by conventional diagnosis models. Such models include probabilistic classifiers and threshold-based decision trees. The models use accurate input-output correlations. However, fuzzy inference simplifies incremental membership assignment and rule-based reasoning in MD-FLF. This enhances the system’s diagnostic ambiguity detection. The framework uses fuzzy rules to represent complicated non-linear interactions between symptoms and diagnostic data. This improves framework interpretation. MD-FLF models’ ambiguity and non-linear relationships between diagnostic inputs and outputs provide interpretable recommendations for complex disorders. Rule-based methods and expert knowledge produce these results. Experimental evaluations showed that MD-FLF improved reliability by 97.68%, uncertainty by 96.84%, ambiguity by 43.56%, patient variability by 98.26%, and diagnostic accuracy by 97.82%. The paradigm addresses uncertainty to increase diagnostic reliability, precision, and confidence while eliminating ambiguity and offering clinical decision-making insights. MD-FLF outperforms deterministic techniques in medical diagnostic decision support systems and is stable and interpretable.

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