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Article | Open Access

Fuzzy computational intelligence in personalized medicine and diagnosis

IT Dept., Chaitanya Bharathi Institute of Technology, Hyderabad 500075, India.
Department of Computational Intelligence, School of Computing, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Chennai 603203, India.
School of Business and Management, Christ university, Bangalore 560029, India.
Department of AI&DS, Panimalar engineering college, Chennai 503200, India.
Department of Computer Science and Engineering, MLR Institute of Technology, Hyderabad 722003, India.
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Abstract

The development of fuzzy computational intelligence (FCI) has emerged as an effective method for personalized medicine and diagnosis. FCI effectively handles uncertainty and imprecision in medical data, facilitating patient-specific treatment recommendations. Conventional diagnostic and treatment methods typically rely on fixed threshold-based approaches, which fail to account for individual variations in patient responses, leading to suboptimal treatment outcomes. This study proposes the personalized treatment recommendation using fuzzy logic (PTR-FC) framework for diabetes (DB) patients to address these challenges. The framework integrates patient-specific data such as blood glucose levels, diet, exercise, and medication history into the fuzzy inference system (FIS), supporting personalized treatment recommendations. The treatment plans are dynamically adapted based on individual patient outcomes using linguistic factors and fuzzy rules (FR). The proposed method dynamically adjusts recommendations in real time, potentially enhancing personalized treatment and improving decision-making in DB management. Additionally, it promotes lifestyle modifications while reducing the risk of medication-induced complications. The effectiveness of the proposed method was compared to conventional methods, demonstrating improved treatment accuracy, increased patient adherence, and reduced adverse health risks. The PTR-FC framework offers a more adaptive and effective approach to DB management, ensuring better patient outcomes.

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Fuzzy Information and Engineering
Pages 472-483

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Cite this article:
Bavirthi SS, Manikandan D, Rajagopal M, et al. Fuzzy computational intelligence in personalized medicine and diagnosis. Fuzzy Information and Engineering, 2025, 17(4): 472-483. https://doi.org/10.26599/FIE.2025.9270073

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Received: 06 March 2025
Revised: 26 March 2025
Accepted: 13 April 2025
Published: 12 December 2025
© The Author(s) 2025.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).