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STAR Guideline Terminology (Ⅲ): Reporting, Evaluation, Dissemination, Implementation and Updating
Medical Journal of Peking Union Medical College Hospital 2025, 16(4): 1018-1025
Published: 03 June 2025
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Objective

To sort, summarize, and introduce key terms related to guideline reporting, evaluation, dissemination, implementation, and updating.

Methods

We systematically searched guideline development manuals and methodological literature from database inception to October 25, 2024. Terms related to guideline reporting, updating, evaluation, and implementation were extracted, standardized, and finalized through a structured consensus process.

Results

A total of 13 guideline manuals and 32 methodological articles were included, yielding 14 core terms with standardized definitions.

Conclusions

This article introduces key terms such as reporting standards, external review, and research gaps across guideline development phases to promote concept application and deepen readers' understanding of guideline development.

Issue
STAR Guideline Terminology(Ⅱ): Clinical Question Formulation, Evidence Retrieval and Appraisal, and Recommendation Development
Medical Journal of Peking Union Medical College Hospital 2025, 16(3): 756-764
Published: 02 April 2025
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Objective

To introduce and analyze guideline terminology related to clinical question formulation, evidence retrieval and appraisal, and recommendation development.

Methods

A systematic search was conducted in guideline development manuals and relevant methodological literature, covering publications up to October 25, 2024. Terminology related to the three aforementioned stages of related to guideline development was extracted from the included literature, standardized, and refined through consensus meetings to finalize a comprehensive terminology list and definitions.

Results

A total of 30 guideline development manuals and 15 methodological articles were included, and 23 core terms were identified.

Conclusions

It is recommended to develop a standardized and scientifically sound guideline terminology system with unified naming, clear definitions, and alignment with the linguistic environment and usage habits in China. At the same time, it is essential to strengthen terminology training for both guideline developers and users based on this system, in order to deepen their correct understanding and proper application of guideline terminology.

Issue
Constructing the Global Health Policy and Management Evidence Clearinghouse to Facilitate Evidence-based Policy Making and Health Governance for Sustainable Development
Medical Journal of Peking Union Medical College Hospital 2025, 16(5): 1309-1314
Published: 25 October 2024
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In order to enhance the transparency of the health policy making process and to ensure the scientific and rigorous of policy making, the concept of evidence-based policy making has been increasingly promoted. By constructing a global health policy and management evidence clearinghouse, which integrates the best practices and scientific research results worldwide, can provide policy makers with the best evidence. Therefore, this paper introduces the objectives, system positioning, evidence scope, technical implementation and functional module of the Global Health Policy and Management Evidence Clearinghouse (HPME), aiming to illustrate its significant value and potential impact in the field of global health policy and management.

Issue
Construction and Testing of Health LifeStyle Evidence (HLSE)
Medical Journal of Peking Union Medical College Hospital 2024, 15(6): 1413-1421
Published: 07 August 2024
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Healthy lifestyles and good living habits are effective strategies and important approaches to prevent chronic non-communicable diseases. With the development of evidence-based medicine, the evidence translation system has made some achievements in clinical practice. There is, however, no comprehensive, professional and efficient system for translating lifestyle evidence globally. Therefore, the Health Lifestyle Evidence (HLSE) Group of Lanzhou University constructed the HLSE Evidence Translation System (https://hlse.cn/), with the aim of synthesizing, evaluating, translating, and applying lifestyle-related evidence resources. This paper aims to introduce the functional module design of the evidence translation system, the system development process and testing, introduce the interface design and function demonstration, and explain the significance of constructing the HLSE.

Issue
Method for Developing Patient Decision Aid in China
Medical Journal of Peking Union Medical College Hospital 2024, 15(6): 1422-1431
Published: 23 May 2024
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Objective

To systematically construct a guideline to provide a methodological guide for researchers to develop patient decision aids.

Methods

Through a literature review of international methodological guidance for developing patient decision aids, sorting out the similarities and differences in the processes and methods for developing patient decision aids, and combining them with the topic discussion of the working group, the initial guideline was drafted.

Results

A total of 13 guidances was included, with the initial version containing 3 phases, 13 steps, and 48 points. We invited 19 multidisciplinary domain experts for forming consensus. The final version of the guideline contains 3 phases, 11 steps, and 24 points.

Conclusions

The guideline has great potential to guide the development of patient decision aids in China and is expected to fill the methodological gap in the field. In the future, several rounds of pilot testing of the guideline based on specific decision issues will be conducted, and the guideline will be further revised and improved.

Issue
Applications and Challenges of Adaptive Platform Trial
Medical Journal of Peking Union Medical College Hospital 2024, 15(5): 1157-1164
Published: 26 January 2024
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Adaptive design, with advantages such as dynamically adjusting trial plans, reducing resource waste, and improving trial efficiency, has broken through the competitive situation of new drug development and gradually met the needs of clinical research. In recent years, the use of adaptive design in platform trials as an innovative research model has added impetus to new drug development. This article outlines the research progress, contents and characteristics, common design types, statistical analysis, and case interpretation of adaptive design, and introduces the concept, types, and applications of adaptive platform trials, with the hope of providing scientific reference for further exploration of clinical trials and new drug development.

Issue
Artificial Intelligence in Shared Decision Making
Medical Journal of Peking Union Medical College Hospital 2024, 15(3): 661-667
Published: 22 August 2023
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Artificial intelligence(AI) empowers the development of the medical industry, providing precise and intelligent assistance for clinical diagnosis, treatment, and rehabilitation.AI has the potential to facilitate shared decision making (SDM), but AI interventions used for SDM are currently in their infancy, presenting both challenges and opportunities. This paper aims to describe the application of AI in SDM, explore the problems and challenges of AI-based decision aid used for SDM, and propose possible solutions, aiming to provide a guide for the development and implementation of AI-based decision aid.

Issue
Vitruvian Plot: A Visual Tool for Intuitive Display of Evidence Summarization Results
Medical Journal of Peking Union Medical College Hospital 2024, 15(3): 668-675
Published: 25 July 2023
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The development of clinical practice guidelines involves a series of evidence-based decision-making processes, of which the formation of recommendations is particularly challenging. It demands decision-makers to have a thorough and precise understanding of the evidence, weigh the potential benefits and risks of interventions, and make valuable judgments and clinical choices. Compared to traditional approaches of presenting evidence information, the use of visualization tools can facilitate the communication and analysis of evidence, simplify information interpretation, and improve the efficiency of decision-making. Based on previousstudies, this paper proposes a visualization tool, vitruvian plot, for summarizing evidence and provides illustrative examples to demonstrate its usage and effects, with the aim of offering valuable guidance for researchers.

Issue
Implementation Evaluation of Clinical Practice Guidelines for Integrative Medicine
Medical Journal of Peking Union Medical College Hospital 2024, 15(2): 413-421
Published: 26 June 2023
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Objective

To systematically assess the applicability of the clinical practice guidelines (CPGs) integrating Chinese and western medicine, thereby providing reference for enhancing their future usability.

Methods

PubMed, Web of Science, Embase, SinoMed, WanFang Data, and CNKI databases were searched for guidelines for the integration of Chinese and western medicine. Supplementary searches of Chinese Medical Association, Chinese Medicine Administration, MedSci websites, Website of China Association of Chinese Medicine, Medlive, Website of Dangdang, Chinese Association of Integrative Medicine and World Federation of Traditional Chinese Medicine Societies were conducted. The search time frame was from inception of the databases to December 31, 2022. Four reviewers independently evaluated the implementability of clinical practice guidelines by using "Clinical Practice Guideline (CPG) implementation evaluation tool".

Results

A total of 61 integrative Chinese and western medicine guidelines were included. Of the guidelines assessed, 9 guidelines(14.75%) exhibited strong implementability, 40(65.57%) demonstrated average implementability, and 12 (19.67%) demonstrated poor implementability. Among the 5 domains, the dimensions of "accessibility" and "implementability" were found to be of high quality, while those of "communication", "ease of identification" and "applicability" were relatively poor. Notably, compared to guidelines published between 2006—2016, those published between 2017—2022 showed improvements in the areas of "identification" and "application".

Conclusions

The implementabilityof the existing clinical practice guidelines of the integrative Chinese and western medicine is average and needs to be improved. In the future, emphasis should be placed on the integration of medical education and research, publicity of the guidelines, continuous medical education and training, a more concise form of recommendations, application of the guidelines by clinicians, and the implementability of the integrative Chinese and western medicine guideline.

Issue
Methods for Developing Rapid and Living Evidence-based Guidelines
Medical Journal of Peking Union Medical College Hospital 2024, 15(1): 183-191
Published: 08 June 2023
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The aims of developing rapid and living guidelines is to keep the recommendations in the guideline up-to-date. Compared with the conventional guideline, the rapid and living guideline can make better use of the existing evidence and apply and transform the evidence in a timely manner. This paper introduces the advantages and usage of rapid and living guidelines, the development process and existing challenges, and offers some insights, in order to provide reference for domestic organizations and scholars engaged in guideline development.

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