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Research Article | Open Access
Ratio-tunable nucleic acid nanohybrids enable precision therapy for esophageal squamous cell carcinoma
Wenyan Yu, Jiahui Su, Yuting Li, [...], Wei Liu, Zigang Dong, Jinjin Shi << Fewer
Published: 19 May 2026
2026, 19(6): 94908592
Research Article | Open Access
Engineered extracellular vesicles with multitargeted anti-microRNA for diabetes-induced cognitive impairment therapy
Xuetao Chen, Haixiang Sun, Zhicong Zhao, [...], Junyi Che, Yan Bi, Yuanjin Zhao, Jin Wang << Fewer
Published: 18 May 2026
2026, 19(6): 94908479
Research Article | Open Access
Targeting inhibiting recruitment of macrophages with siHPX loading activated platelet vesicle for synergizing with PD-1 inhibitors in triple-negative breast cancer
Yongxuan Long, Jie Ling, Wenqian Wei, [...], Yinhua Lv, Xiaoling Guo, Yi Sun, Jinlan Jiao, Anya Buerliesi, Li Li, Yun Zhu, Weijie Zhang << Fewer
Published: 31 December 2025
2026, 19(1): 94907875
Research Article | Open Access
Single-dose cathepsin L CRISPR nanotherapy mitigates PASC-like lung damage in hamsters
Zhifen Cui, Tianxiang Liu, Rebecca Bacon, [...], Yue Zhao, Jeffrey I. Everitt, Jingyue Yan, Lingye Chen, Jiaoti Huang, Hongyan Wang, Yizhou Dong, Victor X. Jin, Shan-Lu Liu, Qianben Wang << Fewer
Published: 19 August 2025
2025, 18(9): 94907695
Review Article
Therapeutic nucleic acids in regenerative medicine and tissue repair
Qimanguli Saiding, Duotian Qin, Soohwan An, [...], Dylan Neal Patel, Muhammad Muzamil Khan, Na Kong, Wei Tao << Fewer
Published: 13 July 2024
2024, 17(10): 8942-8976
Research Article
EGFR-targeted and gemcitabine-incorporated chemogene for combinatorial pancreatic cancer treatment
Miao Xie, Qiushuang Zhang, Yuanyuan Guo, [...], Lijuan Zhu, Xinyuan Zhu, Chuan Zhang << Fewer
Published: 17 November 2023
2024, 17(2): 848-857
Research Article
Natural long-chain saturated fatty acids doped LNPs enabling spleen selective mRNA translation and potent cancer immunotherapy
Fazhan Wang, Meng Zhang, Meiling Tian, [...], Jia Lou, Longze Pan, Xiaoke Gao, Lijing Zhang, Xiaohan Lou, Linyu Zhu, Yuqiao Sheng, Ming Wang, Rui Xue, Wenjing Deng, Shuai Shao, Zhihai Qin << Fewer
Published: 08 September 2023
2024, 17(3): 1804-1817
Research Article
Scalable synthesis of lipid nanoparticles for nucleic acid drug delivery using an isometric channel-size enlarging strategy
Zesen Ma, Haiyang Tong, Sijin Lin, [...], Li Zhou, Demeng Sun, Baoqing Li, Changlin Tian, Jiaru Chu << Fewer
Published: 14 August 2023
2024, 17(4): 2899-2907
Research Article
MicroRNA-208a silencing against myocardial ischemia/reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes
Jianhui Lu, Jiaheng Zhang, Wen Yan, [...], Chenglong Ge, Yang Zhou, Rongying Zhu, Shanzhou Duan, Lichen Yin, Yongbing Chen << Fewer
Published: 13 June 2023
2023, 16(8): 11176-11185
Research Article
Carrier-free programmed spherical nucleic acid for effective ischemic stroke therapy via self-delivery antisense oligonucleotide
Wenyan Yu, Cuiping Xuan, Bingbing Liu, [...], Lei Zhou, Na Yin, Enpeng Gong, Zhenzhong Zhang, Yinchao Li, Kaixiang Zhang, Jinjin Shi << Fewer
Published: 24 May 2022
2023, 16(1): 735-745
Total 13