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The global analysis of the SEIR epidemic model with vaccination and population births
Electronic Research Archive 2025, 33(12): 7289-7309
Published: 03 December 2025
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This paper constructs a Susceptible-Exposed-Infectious-Recovered (SEIR) model that takes into account the dynamic changes in the birth population and includes both vaccinated and unvaccinated populations. The basic reproduction number R 0 is derived, and its global stability is analyzed. It is proven that when R 0 < 1, the disease-free equilibrium point is globally stable. When R 0 > 1, there exist an unstable disease-free equilibrium and a unique endemic equilibrium. Subsequently, we conduct the numerical simulations to validate theoretical results and plot data visualizations for various scenarios. In addition, the parameter sensitivity analysis and the forward bifurcation of the model are performed to examine how each system parameter specifically affects disease transmission. Our results offer practical insights for public health planning, particularly in optimizing vaccination strategies in populations with high birth rates or waning immunity.

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