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Research Article | Open Access

The global analysis of the SEIR epidemic model with vaccination and population births

Zuoheng Chen1,2Youhui Su2( )Qian Wen2Feng-Lan Tu3
School of Science, Shenyang University of Technology, Shenyang 110870, China
School of Mathematics and Statistics, Xuzhou University of Technology, Xuzhou 221018, China
The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China
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Abstract

This paper constructs a Susceptible-Exposed-Infectious-Recovered (SEIR) model that takes into account the dynamic changes in the birth population and includes both vaccinated and unvaccinated populations. The basic reproduction number R 0 is derived, and its global stability is analyzed. It is proven that when R 0 < 1, the disease-free equilibrium point is globally stable. When R 0 > 1, there exist an unstable disease-free equilibrium and a unique endemic equilibrium. Subsequently, we conduct the numerical simulations to validate theoretical results and plot data visualizations for various scenarios. In addition, the parameter sensitivity analysis and the forward bifurcation of the model are performed to examine how each system parameter specifically affects disease transmission. Our results offer practical insights for public health planning, particularly in optimizing vaccination strategies in populations with high birth rates or waning immunity.

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Electronic Research Archive
Pages 7289-7309

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Cite this article:
Chen Z, Su Y, Wen Q, et al. The global analysis of the SEIR epidemic model with vaccination and population births. Electronic Research Archive, 2025, 33(12): 7289-7309. https://doi.org/10.3934/era.2025322

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Received: 09 October 2025
Revised: 17 November 2025
Accepted: 27 November 2025
Published: 03 December 2025
©2025 the Author(s), licensee AIMS Press.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)