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Open Access Issue
Achievements and challenges in primate conservation in China
Journal of Northwest University (Natural Science Edition) 2024, 54(5): 755-766
Published: 25 October 2024
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The dual impact of climate change and human activities has led to a sharp decline in global primate biodiversity. China, which has the most diverse primate species in the northern hemisphere, faces severe ecological threats during its transition from an agricultural to a modern society due to the expansion of modern agriculture, over-exploitation and consumption of natural resources, and excessive land development. In response, China has implemented various ecological conservation measures, including habitat restoration and protection. These efforts have made substantial progress in biodiversity conservation, with certain regions seeing an increase in primate populations. This study conducted a systematic review of historical documents and field research data related to Chinese primates, evaluating the endangered status of primate species in China. Despite improvements in the habitats of most primate species and some population growth, many species still face severe threats, including declining and small populations. Species such as the Myanmar snub-nosed monkey (Rhinopithecus strykeri), eastern black crested gibbon (Nomascus nasutus), and Hainan gibbon (N. hainanus) remain particularly vulnerable due to their limited distribution ranges and extremely small populations. Insufficient scientific data, fragmented information, and a lack of comprehensive studies in conservation biology further exacerbate these challenges. Additionally, there is a notable lack of detailed population monitoring data for species such as the Bengal slow loris (Nycticebus bengalensis), Pygmy slow loris (N. pygmaeus), Indochinese gray langur (Trachypithecus crepusculus), Shortridge’s langur (T. shortridgei), and capped langur (T. pileatus), hindering the development of practical and targeted conservation management strategies. Therefore, for national biodiversity conservation, there is an urgent need for specialized primate surveys, enhanced habitat protection and restoration, and increased focus on cross-border conservation strategies and regional cooperation. Establishing a comprehensive and systematic research database platform, conducting continuous and in-depth research in primate biology. Additionally, strengthening public awareness on wildlife conservation remains essential. Such integrated and systematic efforts will provide scientific support for the current and future conservation and management of primate species in China.

Open Access Research Article Issue
Magnesium-EGCG composite deer antler decellularized ECM hydrogel for diabetic wound healing
Nano Research 2026, 19(1): 94908255
Published: 16 December 2025
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Diabetic wound healing remains a major clinical challenge, primarily due to excessive inflammation, bacterial infection, and impaired angiogenesis. Although various biomaterial-based strategies have been explored, coordinating the complex diabetic wound microenvironment remains difficult to achieve. This study proposes a novel multifunctional hydrogel dressing designed to synergistically address multiple issues. Its key innovation lies in dynamically crosslinking deer antler decellularized matrix (dECM) with oxidized dextran via imine bonds, creating a self-healing hydrogel (dECMH). The deer antler dECM, rich in pro-regenerative components, provides a biomimetic scaffold, while Schiff base crosslinking confers mechanical self-healing and injectability. To further address the complexity of diabetic wounds, magnesium gallate metal-organic frameworks (Mg-EGCG) were embedded within the dECMH network, forming Mg-EGCG@dECMH. This innovative combination enables sustained co-delivery of epigallocatechin gallate (EGCG)—possessing antibacterial, anti-inflammatory, and antioxidant properties—alongside magnesium ions that actively promote cell proliferation and vascular regeneration. In vitro analyses confirmed the hydrogel's capacity to enhance endothelial cell proliferation, boost angiogenesis, and mitigate oxidative stress. In vivo evaluations demonstrated accelerated wound healing, manifested by rapid inflammation resolution, ordered collagen deposition, and stimulated neovascularization. Additionally, the material exhibited excellent biocompatibility, hemostatic effects, and antimicrobial activity. This multifunctional dressing synergistically integrates the inherent bioactivity of unique antler decellularized matrix with the multimodal therapeutic effects of metal-organic nanocomposites, offering an innovative and effective strategy for diabetic wound management.

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