In fact, there are some problems in macro coordination, distribution structure and service efficiency in the purchase of large instruments and equipment. The reason is that the purchase demonstration does not play its due role in the allocation of resources. This article introduces the mechanism design theory in the field of economics, establishes the coordination mechanism of incentive compatibility and information interchange, carries out the comprehensive reform of elements sorting, process re-engineering and data driving to the demonstration work of equipment purchase, and then designs a four-in-one linkage path of “argumentation, budget, procurement and use”. The practice shows that the demonstration reform of large instruments and equipment purchase based on the perspective of mechanism design theory is helpful to solve the problems of structural stagnation and low efficiency in the purchase of large instruments and equipment in universities, and promote the efficiency of capital use and management efficiency.

The safety management of university laboratories cannot be separated from the supervision of government departments. The government should have a full understanding of the level of self-regulation ability of universities and the supervision of internal business departments of the government. The joint supervision of the government and universities is an important measure to improve the safety management ability of university laboratories. According to the theory of responsive regulation, build external and internal cooperative supervision, explore a new model of multi-agent joint supervision of university laboratories, and promote the concerted efforts of all regulatory bodies to improve laboratory safety management capacity.