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Open Access Issue
Application of RW-splint in clinical diagnosis of class Ⅱ 1 malocclusion patients
Journal of Prevention and Treatment for Stomatological Diseases 2017, 25(7): 454-457
Published: 20 July 2017
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Objective

To investigate whether the RW-splint could be used to guide or determine the CR position of the lower jaw so as to provide help for the later diagnostic design.

Methods

20 class Ⅱ malocclusion patients were recruited in orthodontic department of Foshan Stomatological Hospital. They were treated by RW-splint for half a year before orthodontic treatment. The overjet of anterior teeth were recorded before and after treatment.

Results

The overjet of anterior teeth was (6.792 ± 0.795) mm before treatment and (7.720 ± 0.930) mm after half a year's treatment. The overjet of anterior teeth had significant difference (t=6.319, P < 0.01). The overjet change of anterior teeth between before treatment and half year after treatment was (0.928 ± 0.657) mm.

Conclusion

The RW-splint wearing before treatment can be used to guide or determine the mandible in the CR position.

Open Access Issue
Three dimensionally reconstructed of the mandibular incisive canal by CBCT
Journal of Prevention and Treatment for Stomatological Diseases 2017, 25(8): 506-509
Published: 20 August 2017
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Objective

To find out the existence of Mandibular Incisive Canal (MIC) through CBCT scanning and measure its 3D relationship with the surrounding tissue, so as to provide protection for the operation in submental area.

Methods

CBCT images of 100 patients were measured and three dimensionally reconstructed. The measurement include following items, the existence of the MIC; vertical and horizontal diameter of MIC; vertical distance from MIC to the mandibular buccal and lingual wall; to the root apex, to the inferior border of mandible and alveolar crest in corresponding points (the mandibular first premolar, canine and incisor).

Results

the MIC was 100% visible in CBCT. The mean distance between MIC and buccal bone plate and lingual bone plate was 3.52 ± 0.54 mm and 5.37 ± 0.25 mm. The average distance from the inferior border of the mandible, the apex of the root and the crest of the alveolar bone was 10.44 ± 0.61 mm、10.57 ± 0.76 mm and 20.21 ± 0.83 mm relatively. The distance from MIC to the inferior border of the mandible in male was 10.70 ± 0.43 mm and 10.17 ± 0.63 mm in female, P<0.05.

Conclusion

The detection rate of MIC is high and there are many variations. It was suggested that the location and size of the MIC should be checked in CBCT in each patient before operation, which is helpful to avoid surgical complications in submental area.

Open Access Issue
Analysis of crown-root morphology in canines based on cone-beam computed tomography
Journal of Prevention and Treatment for Stomatological Diseases 2020, 28(6): 372-376
Published: 20 June 2020
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Objective

To compare the morphology of the crown roots of upper and lower canines in patients with skeletal Class Ⅰ, Ⅱ, and Ⅲ malocclusions by CBCT and to provide guidance for the clinical treatment of orthodontics.

Methods

Randomly selected patients with permanent occlusal malocclusion who had undergone CBCT and X - ray skull lateral radiographs were Classified according to the ANB angle size: group Ⅰ, group Ⅱ, and group Ⅲ. Three-dimensional reconstruction was used to obtain the median sagittal section images of the right upper and lower canines. The crown root angle, crown root deflection distance, and lip tangent angle at the center of the clinical crown were used as indicators for measurement and analysis with the use of AutoCAD software.

Results

The difference in the crown-root skew distance between different sagittal face types, including upper canines (F=3.335, P=0.042), lower canines (F=3.745, P=0.029) crown root angles and upper canines (F=3.312, P=0.043), and lower canines (F=3.641, P=0.032), was statistically significant (P < 0.05). The crown root angle of the maxillary canine in group Ⅰ was larger than that in group Ⅱ, and the deflection distance of the crown root was negative and the absolute value was lager in group Ⅰ than in group Ⅱ (P < 0.05). The deflection distance was positive and greater in group Ⅲ than in groups Ⅰ and Ⅱ (P < 0.05). There was no significant difference in the maxillary canine crown-labial tangent angle between the different sagittal facial misalignment groups (P > 0.05).

Conclusion

Differences in the morphology of canines were found among subjects with skeletal Class Ⅰ, Ⅱ, and Ⅲ malocclusions. The root of the upper canine in Class Ⅰ malocclusions was relatively closer to the labial side of the crown than that in Class Ⅱ malocclusions. The root of the lower canine in Class Ⅲ malocclusions was the closest to the lingual side of the crown among the three Classes.

Open Access Issue
Clinical comparison of space closure with sliding mechanism between self ligating bracket and twin brackets
Journal of Prevention and Treatment for Stomatological Diseases 2016, 24(6): 349-351
Published: 20 June 2016
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Objective

To compare the the rate of en-masse space closure with sliding mechanics between 3M SmartClip self-ligating brackets and 3M Gemini MBT twin brackets in the first premolar extraction patients.

Methods

20 Class I malocclusion patients who need first premolar extraction treatment were selected. One arch side of the second premolar and first molar were bonded with 3M self-ligating brackets and the other side bonded with Gemini MBT twin brackets. After leveling and alignment, 0.48 mm × 0.64 mm (0.019 inch × 0.025 inch) stainless steel wire and nickel titanium coil springs were used to close the space. An average rate of space closure per month (mm/month) was calculated in each side.

Results

The median rates of tooth movement for the SmartClip bracket side (1.03 mm per month) and the Gemini MBT twin brackets side (1.00 mm per month) were not significantly different (t = 0.70, P = 0.48).

Conclusion

There was no significant difference in the rate of en-masse space closure between SmartClip brackets and Gemini MBT twin brackets.

Open Access Review Article Issue
Application of telomere biology and telomerase in mesenchymal stem cells
Nano TransMed 2022, 1(2–4): e9130007
Published: 08 September 2022
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With the increasing understanding of mesenchymal stem cells (MSCs), their potential in tissue engineering and regenerative medicine has attracted more attention. However, some important problems need to be solved before clinical application, such as low amplification efficiency, inconsistent cell product quality, and unsatisfactory survival rate at the receptor site. Telomeres act as a clock, and they shorten when cells divide. The main mechanism for reversing telomere length is telomerase. Furthermore, telomerase is involved in antioxidation, antiapoptosis, immunological modulation, and other noncanonical processes in addition to proliferation-related tasks. Therefore, it is necessary to understand the telomere biology and telomerase of MSCs to improve their proliferation, performance stability, and antiscavenging ability. This review summarizes the progress of telomerase biological function and mechanism in MSCs, and discusses the current situation and deficiency of telomerase-related application in MSCs.

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