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Article | Open Access

An efficient fuzzy logic-integrated hybrid deep learning framework for medical diagnosis

Department of Computer Science with Cyber Security, Dr. SNS Rajalakshmi College of Arts and Science, Coimbatore 600049, India.
School of Business and Management, Christ University, Bangalore 600871, India.
Department of Information Technology, Dr. Mahalingam College of Engineering and Technology, Pollachi 642003, India.
Department of Information Science and Engineering, New Horizon College of Engineering, Bangalore 600671, India.
Department of AI&DS, Panimalar Engineering College, Chennai 600123, India.
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Abstract

Medical diagnosis involves analyzing symptoms, test results, and patient histories, but uncertainty from vague symptoms and incomplete records complicates the process. Fuzzy logic-based systems address this issue but often depend on manual rule creation, which is time-consuming. This research proposes a hybrid approach integrating fuzzy logic with deep learning techniques (FL-DLT) for intelligent diagnosis. The framework combines adaptive neuro-fuzzy inference system (ANFIS) for handling uncertainty with convolutional neural networks (CNNs) for extracting features from medical images like X-rays and MRIs. ANFIS models relationships between symptoms, results, and diagnoses, while CNNs analyze medical images. Experimental results show high accuracy and reliability, even with noisy or incomplete data. The proposed approach can improve diagnostic accuracy and efficiency, supporting clinicians in decision-making. Key contributions include the development of the FL-DLT framework and its evaluation using a large dataset of patient records and medical images. Additionally, the research offers insights into the application of fuzzy logic and deep learning in medical diagnosis, highlighting their potential to enhance diagnostic outcomes and efficiency in clinical practice.

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Fuzzy Information and Engineering
Pages 1-18

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Cite this article:
Saranya R, Rajagopal M, Ramprasath J, et al. An efficient fuzzy logic-integrated hybrid deep learning framework for medical diagnosis. Fuzzy Information and Engineering, 2026, 18(1): 1-18. https://doi.org/10.26599/FIE.2025.9270072

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Received: 13 February 2025
Revised: 17 March 2025
Accepted: 03 April 2025
Published: 09 May 2026
© The Author(s) 2026.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).