This work develops a stochastic model to explore the dynamical behaviour of hepatitis B virus (HBV) infection by incorporating virus-to-cell transmission, cell-to-cell transmission, and the cytotoxic T lymphocyte (CTL) immune response under Lévy noise, which represents sudden environmental perturbations. The model is formulated, and its feasibility is investigated. The study is further enriched by proving the uniqueness, existence, and positivity of the global solution. A sufficient extinction condition is derived by using a combined infected-virus Lyapunov functional. In addition, a conditional sufficient criterion for long-term average persistence is established under bounded-state dynamics. The extinction result shows that infected hepatocytes and free virus particles vanish when the corresponding sufficient extinction condition is satisfied, whereas persistence is obtained under the boundedness assumption on the normalization factor and the condition
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AIMS Mathematics 2026, 11(7): 21036-21068
Published: 15 July 2026
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