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Open Access Original Research Issue
Randomized controlled trial of sequential motor imagery–based brain–computer interface and scalp acupuncture for post-stroke motor recovery with a multimodal neuroimaging case exploration
Journal of Neurorestoratology 2026, 14(3)
Published: 01 June 2026
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Background

To investigate the clinical efficacy of motor imagery (MI)-based brain–computer interface (BCI) combined with scalp acupuncture in upper limb motor rehabilitation of post-stroke hemiplegia patients.

Methods

Sixty-two patients with post-stroke hemiplegia were randomly assigned to an Acu-group (n = 31) or a BCI-Acu group (n = 31). Both groups received conventional medication and comprehensive rehabilitation training. Additionally, both groups underwent scalp acupuncture. The BCI-Acu group also received MI-based BCI training sequentially prior to scalp acupuncture. All interventions were conducted over a 4-week period. Fugl-Meyer Assessment of upper limb (FMA-UL), Wolf Motor Function Test (WMFT), Modified Ashworth Spasticity Scale (MAS), National Institutes of Health Stroke Scale (NIHSS), and Modified Barthel Index (MBI) scores were compared before and after treatment.

Results

After treatment, both groups showed increased FMA-UL, WMFT, and MBI scores (p < 0.05) and decreased MAS and NIHSS scores (p < 0.05). The improvements in FMA-UL, WMFT, and MBI scores were greater in the BCI-Acu group than in the Acu-group (p < 0.05).

Conclusion

Our findings indicate that, in conjunction with conventional pharmacotherapy and comprehensive rehabilitation, the sequential administration of BCI training prior to scalp acupuncture facilitates neurological recovery in patients after ischemic stroke. Moreover, this sequential protocol was superior to scalp acupuncture monotherapy for improving upper limb motor function and self-care capacity, highlighting its promise for widespread clinical application.

Open Access Issue
The impact of penetrating needling combined with sling exercise therapy on lower limb motor and balance function in post-stroke hemiplegic patients
Acupuncture Research 2026, 51(6): 749-757
Published: 13 March 2026
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Objective

To observe the effects of penetrating needling combined with sling exercise therapy (SET) on lower limb motor function, balance, and spasticity in patients with post-stroke hemiplegia.

Methods

Patients with post-stroke hemiplegia were randomly divided into a control group (33 cases, 1 dropout) and a penetrating needling group (33 cases, 1 dropout). All participants received standard medical treatment, rehabilitation training, and routine acupuncture as baseline therapy. The control group received additional SET, while the penetrating needling group received additional SET combined with penetrating needling therapy. The penetrating needling technique was applied from Ququan (LR8) to Xiyangguan (GB33), from Yanglingquan (GB34) to Yinlingquan (SP9), from Fuyang (BL59) to Jiaoxin (KI8), and from Qiuxu (GB40) to Zhaohai (KI6). Outcome measures, including the Fugl-Meyer assessment of lower extremity motor function (FMA-L), Berg balance scale (BBS), modified Ashworth scale (MAS), and gait analysis data (assessed using a force plate system), were evaluated before and after treatment.

Results

After treatment, both groups showed significant improvements: increased FMA-L and BBS scores, decreased MAS scores, reduced postural sway parameters (eyes-open ball length, eyes-open ellipse area, eyes-closed ball length, and eyes-closed ellipse area), decreased load on the healthy side and medial-lateral load asymmetry, and increased step frequency, step speed, and load on the affected side (all P<0.05). The penetrating needling group demonstrated superior improvements in all measures compared to the control group (P<0.05).

Conclusion

The combination of penetrating needling and SET helps balance the medial-lateral plantar load distribution between the healthy and affected sides in post-stroke hemiplegic patients, shifts the center of gravity toward the midline, enhances standing stability, improves motor and balance functions, and alleviates spasticity.

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