The ultimate objective of manufacturing is to construct a universal tool system capable of systematically overcoming the spatiotemporal constraints facing humanity. In this context, Extreme Manufacturing (EM) has emerged. The essence of EM lies in harnessing unconventional scientific principles with the explicit goal of transcending established limits. Consequently, EM is not merely a linear extension of traditional manufacturing paradigms but a systemic revolution designed to challenge physical and engineering boundaries. Characterized by extreme environments, extreme scales, superior performance, profound interdisciplinarity, and massive data, this paradigm effectively expands human capabilities across spatial, temporal, and cognitive dimensions. Ultimately, EM will drive sustainable technological progress for human civilization and deepen our mastery over the material world.