A Closed-Space Model was constructed using steel plates to examine the influence of afterburning energy load generated by explosive detonation products on the damage characteristics of confined space. Additionally, the quasi-static pressure in the confined space was simplified by applying the energy conservation law. Relying on the adiabatic index of the mixture of detonation products and air, as well as the complete afterburning degree of detonation products, a simulation method for the afterburning effect was proposed. This method was used to calculate the afterburning energy of detonation products and determine the beginning and ending times of the afterburning effect. The numerical simulation of implosion damage in a confined space was carried out by this method. The implosion simulation considering the afterburning energy load was performed by employing two simulation methods: constant reaction rate and linearly increasing reaction rate. The results were compared with the implosion simulation results without considering the afterburning effect. The influence and degree of change of the afterburning effect on the implosion damage characteristics were analyzed. It is found that the afterburning effect with different reaction rates has a significant influence on the detonation damage characteristics, except for the temperature, in confined spaces. Moreover, the enhancement effect of the constant reaction rate is the most significant. It increased the velocity and acceleration loads under implosion in the confined space by 42.67% and 71.21%, respectively. The overpressure and quasi-static pressure were increased by 74.42% and 74.95%, respectively, and the kinetic energy was increased by approximately 212%. The proposed simulation method for the afterburning effect can better simulate the dynamic response of implosion ruin in confined spaces and provides a more accurate simulation method of the afterburning effect for the design and evaluation of explosion-proof structures.