This study explores the evolution and application of integral transformations, initially rooted in mathematical physics but now widely employed across diverse mathematical disciplines. Integral transformations offer a comprehensive framework comprising recurrence relations, generating expressions, operational formalism, and special functions, enabling the construction and analysis of specialized polynomials. Specifically, the research investigates a novel extended family of Frobenius-Genocchi polynomials of the Hermite-Apostol-type, incorporating multivariable variables defined through fractional operators. It introduces an operational rule for this generalized family, establishes a generating connection, and derives recurring relations. Moreover, the study highlights the practical applications of this generalized family, demonstrating its potential to provide solutions for specific scenarios.