A number of small uranium deposits, occurrences and anomalies have been discovered in the exploration of the Junggar Basin, two-thirds of which are located in the southern edge of the basin. But no uranium deposits of medium size or above have been found, and no fundamental breakthrough in mineral search has been achieved. In order to understand the deposition and distribution pattern of sandstone type uranium ore in the southern margin of Junggar Basin, objectively evaluate the mineralization potential and uranium metallogenic prospect, guided by stratigraphic stratigraphy, sedimentology and hydrogenic uranium ore theory, after analyzing the data from field research drilling and logging, and analyzing various strata in the southern margin of the basin, we focused on the Middle Jurassic Toutunhe Formation (J₂t) in the Liuhuanggou area, and established the isochronous stratigraphic bridge of the Toutunhe Formation in this area. Then, we analyzed the material source direction, sand body thickness, sedimentary environment and depositional system of the Toutunhe Formation during the depositional period. Finally, the spatial spreading and the development characteristics of the main sand body of the Tutunhe Formation have been clarified. Combined with the distribution of known uranium mineralization and the geochemical properties of the petrographic phases of the Tourtunhe Formation, it is concluded that the Tourtunhe Formation can be subdivided into the lower sub-section (J₂t^1-1), the upper sub-section (J₂t^1-2) of the lower section, the lower sub-section (J₂t^2-1) and the upper sub-section (J₂t^2-2) of the upper section in the Liuhuanggou area, which is a braided river-quadrangular river sedimentary system from the bottom up. The large braided river sand body in J₂t^1-1 is the most favorable mineralization formation. And J₂t^2-1 is also a potential prospective formation. Secondly, the sand body spreads along the NWW direction and gradually thins toward NE, which is consistent with the trend of the main mineralization, and the material source is mainly from the southwest of the area. Thirdly, the uranium mineralization is obviously influenced by the late basin modification and the oil and gas action, with moderate stripping. Further, it is controlled by the two flanks of the back-sloping tectonic core stratigraphy of the neotectonic fold zone. Therefore, it is believed that the Toutunhe Formation in the Liuhuanggou area has favorable conditions and potential for ore-forming and search of sandstone-type uranium.