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Open Access Issue
Antioxidant and Immunological Activities of Sacha Inchi Soluble Dietary Fiber
Food Science 2022, 43(13): 131-139
Published: 15 July 2022
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Sacha inchi soluble dietary fiber (SISDF) was evaluated for its antioxidant and immunological activity. The structure of SISDF was identified by ion chromatography, gel chromatography and Fourier transform infrared (FTIR) spectroscopy. The results showed that the weight-average molecular mass of SISDF was 401479 Da, which was found to be a large polysaccharide with pyranose as the main chain. The monosaccharide composition analysis showed that SISDF consisted of galacturonic acid (46.49%), rhamnose (18.95%), xylose (17.60%) and galactose (11.25%). At 2 mg/mL, SISDF scavenged 68.57% of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, 69.83% of hydroxyl radical and 70.35% of 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation. At concentrations of 62.5–1000 μg/mL, SISDF enhanced the proliferative and phagocytic activities of RAW264.7 macrophages significantly (P < 0.01) and increased the secretion levels of NO, interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α factors in RAW264.7 macrophages. Therefore, sacha inchi soluble dietary fiber has good antioxidant and immune activity, and thus has the potential to be developed as a natural food antioxidant and anti-inflammatory nutraceutical.

Open Access Review Issue
Progress in Research on Composition, Structure, Functions and Mechanism of Action of Radix Puerariae Isoflavones
Food Science 2023, 44(1): 353-361
Published: 15 January 2023
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Radix Puerariae (RP) is an important medicinal and edible food in China. The country has an abundant RP output and a large number of RP consumers. Isoflavones are the most abundant and bioactive ingredients in RP. This article comprehensively reviews the composition and structure of isoflavones from RP, and systematically expounds their functions such as anti-hypertension, anti-hyperlipidemia, anti-hyperglycemia and antioxidant activity, alleviating a hangover, liver protection, alleviating post-menopausal osteoporosis and improving cognition as well as the underlying mechanism of action. The current research hotspots and problems existing in the field of research on RP isoflavones and their significance to the development of drugs and functional foods containing RP isoflavones are also proposed. We believe that this review will provide useful ideas and guidance for the basic research on RP and the commercialization of research achievements in this field.

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