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Open Access Review Article Issue
Childhood myopia in the modern environment: modifiable risk factors and evidence-based prevention
International Journal of Ophthalmology 2026, 19(9): 1847-1857
Published: 18 September 2026
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This review aimed to summarize modifiable environmental and lifestyle risk factors for childhood myopia and evaluate evidence-based preventive strategies for family, school, and public health practice. Following the PRISMA-ScR framework, relevant studies on children aged 5–18y published up to January 2026 were retrieved from mainstream databases, and eligible literature was synthesized according to study design and evidence level. Reduced outdoor activity, excessive near-work and screen exposure, urban residence, insufficient sleep, and gene-environment interaction are major risk factors for childhood myopia. Daily outdoor activity of 1–2h or longer confers protective effects via promoting retinal dopamine release and inhibiting axial elongation, whereas prolonged close work and excessive screen time notably elevate myopia risk. Optimizing outdoor time, regulating ocular use habits, ensuring sufficient sleep, and implementing school-based interventions are core evidence-based preventive measures, and wearable devices and objective biomarkers can facilitate behavioral management and intervention evaluation. In conclusion, childhood myopia is influenced by multiple adjustable factors; increased outdoor exposure is the most effective preventive measure, and combined behavioral and policy interventions are essential to curb the global prevalence of childhood myopia and prevent subsequent severe visual complications.

Open Access Clinical Research Issue
A surgical alternative of fusiform penetrating keratoplasty for the management of severe infectious keratitis
International Journal of Ophthalmology 2024, 17(8): 1431-1436
Published: 18 August 2024
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AIM

To describe the surgical procedure of fusiform penetrating keratoplasty (FPK) using multiple trephines of different sizes for treating patients with severe infectious keratitis.

METHODS

Fourteen eyes underwent FPK, and 15 eyes received conventional penetrating keratoplasty (PK) were included in the study. The best-corrected visual acuity (BCVA), refractive outcomes, endothelial cell density, and postoperative complications were recorded.

RESULTS

The FPK group was followed for an average of 15.3±2.1mo, whereas the PK group was followed for 16.1±1.9mo. The corneal ulcers were elliptical-shaped in all 14 eyes in the FPK group. The mean BCVA (logMAR, 0.26±0.13) showed no statistically significant differences from that in the PK group (logMAR, 0.21±0.12, P>0.05) at 1y after surgery. But the mean curvature, mean astigmatism, and mean spherical equivalent in the FPK group were lower than those in the PK group (P<0.05). Peripheral anterior synechia was observed in one patient in the FPK group, whereas 6 patients in the PK group. Suture loosening and neovascularization were observed in 4 and 5 eyes in the PK group, respectively. No graft immune rejection or elevation of intraocular pressure was observed in the two groups.

CONCLUSION

For patients with elliptical-shaped corneas or corneal ulcers, FPK can avoid disrupting of corneal limbus, reduce the risk of postoperative complications, and can result in satisfactory visual quality.

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