Spectra of network related graphs have numerous applications in computer sciences, electrical networks and complex networks to explore structural characterization like stability and strength of these different real-world networks. In present article, our consideration is to compute spectrum based results of generalized prism graph which is well-known planar and polyhedral graph family belongs to the generalized Petersen graphs. Then obtained results are applied to compute some network related quantities like global mean-first passage time, average path length, number of spanning trees, graph energies and spectral radius.