Parkinson's disease (PD) is mainly characterized by changes of firing and pathological oscillations in the basal ganglia (BG). In order to better understand the therapeutic effect of noninvasive magnetic stimulation, which has been used in the treatment of PD, we employ the Izhikevich neuron model as the basic node to study the electrical activity and the controllability of magnetic stimulation in a cortico-basal ganglia-thalamus (CBGT) network. Results show that the firing properties of the physiological and pathological state can be reproduced. Additionally, the electrical activity of pyramidal neurons and strong synapse connection in the hyperdirect pathway cause abnormal
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Open Access
Research Article
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Electronic Research Archive 2022, 30(6): 2054-2074
Published: 15 June 2022
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