In the face of rigid food supply constraints, intensifying resource and environmental pressures, and rising demands for nutritional health, there is an urgent need for a sustainable, health-oriented modern food system. This review synthesizes key innovation trends in future foods, focusing on three major directions: (ⅰ) exploration of novel food resources such as alternative proteins and functional carbohydrates offers diverse new pathways for food supply and nutritional enhancement; (ⅱ) cutting-edge production and processing technologies, including synthetic biology and micro/nanotechnology, are driving food production toward efficient resource utilization and functional controllability; and (ⅲ) the deepening of the precision nutrition concept facilitates the shift of future food design from standardization to personalization. By summarizing emerging resources, technologies, and concepts in the field of future foods, this review aims to provide scientific insights for the sustainable and healthy development of the global food industry.
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Open Access
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Open Access
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Soluble dietary fiber (SDF) was extracted from Herba Lophatheri by enzymatic extraction, ball milling-assisted enzymatic extraction, alkaline-assisted enzymatic extraction, and ball milling combined with alkaline-assisted enzymatic extraction. The yield of SDF was determined, the four SDFs were characterized by high performance liquid chromatography (HPLC), nano-laser particle size analyzer, rheometer, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffractometry (XRD) and differential scanning calorimetry (DSC), and their water-holding capacity, oil-holding capacity, and antioxidant activity were analyzed and compared. The results suggested that all SDFs had the typical structure of polysaccharides and the same crystal types as cellulose, but their monosaccharide composition and microstructure were different. SDF extracted by ball milling combined with alkaline-assisted enzymatic extraction had the highest yield ((30.03 ± 1.03)%) and water-holding capacity ((4.86 ± 0.1) g/g), high viscosity, and the lowest zeta potential ((-22.83 ± 1.95) mV). Besides, it had a loose porous structure, and potent 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation scavenging activity ((49.40 ± 0.93)%), indicating strong water-binding capacity, antioxidant activity, and gel-forming capacity.
Open Access
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To investigate the ameliorative effect and mechanism of Parabacteroides distasonis on cognitive impairment caused by type 2 diabetes mellitus (T2DM).
Ten-week-old db/db mice were administered with P. distasonis (1 × 109 CFU/mL) by gavage for 5 weeks. During this period, the body mass and insulin resistance of all mice were monitored. Behavioral tests were conducted to evaluate changes in spatial memory, recognition memory, and working memory capacity. Furthermore, serum levels of insulin, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) were measured, along with morphological and inflammatory changes in liver, brain, and colon tissues. Additionally, changes in serum bile acids and the mRNA expression of genes associated with bile acid metabolism were examined.
Intervention with P. distasonis effectively regulated blood glucose homeostasis and insulin resistance in db/db mice. It reduced the mass of adipose tissue, decreased hepatic fat accumulation, and lowered serum concentrations of TC, LDL-C and TG. The intervention restored colonic morphology, protected intestinal barrier integrity, and reduced intestinal inflammation. It also promoted bile acid production and activated bile acid metabolism-related signaling pathways. Meanwhile, it suppressed cerebral neuroinflammation and oxidative stress, repaired neuronal damage, and significantly alleviated cognitive impairment.
P. distasonis intervention can lower blood glucose, alleviate insulin resistance, and mitigate glucose and lipid metabolic disorders as well as cognitive dysfunction induced by T2DM, showing potential as a new generation of probiotics for diabetic management.
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