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Dynamics and analysis of COVID-19 disease transmission: The effect of vaccination and quarantine
Mathematical Modelling and Control 2023, 3(3): 192-209
Published: 15 September 2023
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In this study, a fractional-order model for COVID-19 disease transmission is proposed and studied. First, the disease-free equilibrium and the basic reproduction number, R 0 of the model has been communicated. The local and global stability of the disease-free equilibrium have been proved using well-constructed Lyapunov functions. Moreover, a normalized sensitivity analysis for the model parameters has been performed to identify their influence on R 0 . Real data on COVID-19 disease from Wuhan in China has been used to validate the proposed model. Finally, a simulation of the model has been performed to determine the effects of memory and control strategies. Overall, one can note that vaccination and quarantine have the potential to minimize the spread of COVID-19 in the population.

Open Access Research Article Issue
Global stability analysis of a COVID-19 epidemic model with incubation delay
Mathematical Modelling and Control 2023, 3(1): 23-38
Published: 15 March 2023
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In this paper, we propose, analyze and simulate a time delay differential equation to investigate the transmission and spread of Coronavirus disease (COVID-19). The basic reproduction number of the model is determined and qualitatively used to investigate the global stability of the model's steady states. We use numerical simulations to support the analytical results in the study. From the simulation results, we note that whenever the basic reproduction number is greater than unity, the model solutions will be associated with periodic oscillations for a considerable time scale from the start before attaining stability. This suggests that the inclusion of the time delay factor destabilizes the endemic equilibrium point leading to periodic solutions that arise due to Hopf bifurcations for a certain time frame.

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