Despite the blitz on chemical-based fertilizers, the transition towards the bio-based fertilizers may subvert fossilfuels-based fertilizers. Research efforts are perpetrated to contend the transition towards sustainable agriculture, thus, enhancing the bio-based economy. Bioprotective agents are key players for alternative farming as environmentally-friendly applications. This mini-review provides a consolidated briefing of lactic acid bacteria production with the main focus on their impact on human health.