The biharmonic equation/eigenvalue problem is one of the fundamental model problems in mathematics and physics and has wide applications. In this paper, for the biharmonic eigenvalue problem, based on the work of Gudi [Numer. Methods Partial Differ. Equ., 27 (2011), 315-328], we study the a posteriori error estimates of the approximate eigenpairs obtained by the Ciarlet-Raviart mixed finite element method. We prove the reliability and efficiency of the error estimator of the approximate eigenfunction and analyze the reliability of the error estimator of the approximate eigenvalues. We also implement the adaptive calculation and exhibit the numerical experiments which show that our method is efficient and can get an approximate solution with high accuracy.