As two of the largest economies and countries in the world, the People’s Republic of China (China) and the United States of America (U.S.) both have enormous resources and innovative talents in a number of sectors. Cooperation between both sides will be hugely beneficial to the world population, and this is especially the case with healthcare. The U.S.-China Track Ⅱ Dialogue on Healthcare was set up as a forum to discuss and engage ideas on this very topic. In this dialogue, Dr. Qun Yan, head of the hLife Editorial Office engages in a dialogue with Professor Mark McClellan, the Director of the Duke-Margolis Institute for Health Policy at Duke University and U.S. Co-Chair of the Track Ⅱ Dialogue on Healthcare, Professor Gordon G Liu, Professor at Peking University and the Dean of the PKU Institute for Global Health and Development and Co-Organizer of the Track Ⅱ Dialogue, Mr. Stephen Orlins, President of the National Committee on U.S.-China Relations and a Co-Organizer of the Track Ⅱ Dialogue, and Professor George Fu Gao, Academician at the Chinese Academy of Sciences and former Director of the Chinese Center for Disease Control and Prevention. They discuss how and why the Track Ⅱ Dialogue was created, the successes and developments of the dialogues, and what the future of American-Chinese health collaboration looks like.