In recent years, the rapid development of Internet technology has constantly enriched people’s daily life and gradually changed from the traditional computer terminal to the mobile terminal. But with it comes the security problems brought by the mobile terminal. Especially for Android system, due to its open source nature, malicious applications continue to emerge, which greatly threatens the data security of users. Therefore, this paper proposes a method of trusted embedded static measurement and data transmission protection architecture based on Android to reduce the risk of data leakage in the process of terminal storage and transmission. We conducted detailed data and feasibility analysis of the proposed method from the aspects of time consumption, storage overhead and security. The experimental results show that this method can detect Android system layer attacks such as self-booting of the malicious module and improve the security of data encryption and transmission process effectively. Compared with the native system, the additional performance overhead is small.