At present, the performances of perovskite solar cells (PSCs) are comparable to that of crystalline silicon solar cells, but their relatively poor stabilities are not conducive to industrial application. In this paper, the factors causing the instabilities of perovskite nanocrystals and the main strategies to improve the stability of corresponding solar cells are introduced, while the latest research progresses of organosilicon in PSCs are evaluated. The influence mechanism of silane coupling agent, silicone resin and other organosilicon molecules on the properties of perovskite films (such as morphology, trap state density, carrier transport and ion migration, etc.) and the performances of devices (such as power conversion efficiency and stability, etc.) will be discussed in detail. Finally, the development trend of self-crosslinked organosilicon materials in efficient and stable PSCs are prospected, aiming to provide reference for accelerating the industrialization of PSCs.