Aiming at the teaching goal of cultivating “applied talents ”, the idea of college physics and experiment curriculum reform based on “four-dimensional” ability was put forward in this paper. A “four-in-one” progressive curriculum system has been constructed, implementing a tiered and graded teaching model. The teaching content has been restructured in a modular and hierarchical way, adopting the teaching method of “problem+research-oriented”. This paper makes a useful attempt to explore the construction of college physics and experimental courses in applied undergraduate colleges with certain characteristics. In recent years, based on the “four-dimensional” ability-oriented teaching practice, undergraduates with different professional backgrounds have achieved remarkable results in subject competitions, and a series of achievements have been made in teaching achievement awards, teaching reform projects, and teaching papers.