Under the background of the construction of “new engineering” and the training mode of large-scale talents, combined with the characteristics of national defense, the orientation of subjects and the existing experimental teaching and scientific research conditions, we explored and reformed the curriculum system of experimental teaching for undergraduate majors of Applied Physics in our university. It mainly includes the construction of a professional experimental teaching system with national defense characteristics, the design of research-oriented modular series of experiments and the implementation of diversified assessment. Through exploration and practice, it has promoted the construction of national and provincial first-class undergraduate majors, improved students' innovation ability, cooperation ability and practical ability, stimulated military feelings, cultivated the spirit of scientists, and significantly improved students' comprehensive quality.