Sort:
Open Access Issue
Advanced Deep Neural Network with Unified Feature-Aware and Label Embedding for Multi-Label Arrhythmias Classification
Tsinghua Science and Technology 2025, 30(3): 1251-1269
Published: 30 December 2024
Abstract PDF (6.2 MB) Collect
Downloads:0

Multi-label arrhythmias classification is of great significance to the diagnosis of cardiovascular disease, and it is a challenging task as it requires identifying the label subset most related to each instance. In this paper, by integrating a deep residual neural network and auto-encoder, we propose an advanced deep neural network (DNN) framework with unified feature-aware and label embedding to perform multi-label arrhythmias classification involving 30 types of arrhythmias. Firstly, a deep residual neural network is built to extract the complex pathological features from varying-dimensional electrocardiograms (ECGs). Secondly, the mean square error loss is adopted to learn a latent space associating the deep pathological features and the corresponding label data, and then to achieve unified feature-label embedding. Thirdly, the label-correlation aware loss is introduced to optimize the auto-encoder architecture, which enables our model to exploit label-correlation for improved multi-label prediction. Our proposed DNN model can allow end-to-end training and prediction, which can perform feature-aware, label embedding, and label-correlation aware prediction in a unified framework. Finally, our proposed model is evaluated on the currently largest public dataset worldwide, and achieves the challenge metric scores of 0.492, 0.495, and 0.490 on the 12-lead, 3-lead, and all-lead version ECGs, respectively. The performance of our approach outperforms other current state-of-the-art methods in the leave-one-dataset-out cross-validation setting, which demonstrates that our approach has great competitiveness in identifying a wider range of multi-label arrhythmias.

Open Access Issue
Wearable Continuous Blood Pressure Monitoring Based on Pulsatile Cycle Volume Adjustment Method
Tsinghua Science and Technology 2025, 30(2): 650-669
Published: 09 December 2024
Abstract PDF (11.8 MB) Collect
Downloads:10

Accurate and portable Blood Pressure (BP) monitoring is vital for managing cardiovascular diseases. However, existing wearable continuous BP monitoring technologies are often inaccurate and rely on external calibration, limiting their practical application in continuous BP monitoring. To address this challenge, we have developed a Wearable continuous non-invasive BP Monitor (WeBPM) equipped with a finger cuff sensor, capable of monitoring BP continuously and accurately within medical-grade precision. WeBPM integrates advanced finger oscillographic BP measurement technology to provide reliable self-calibration functionality. Moreover, Pulsatile Cycle Volume Adjustment Method (PCVAM) we proposed for the closed-loop phase can continuously track changes in vasomotor tone under a controlled frequency based on pulsatile cycles, thereby enabling continuous BP measurement. In comparative experiments with the Nexfin monitor, WeBPM demonstrates excellent performance in induced dynamic BP experiments, with measurement errors of (–1.4 ± 6.24) mmHg for Systolic BP (SBP) and (–0.82 ± 4.83) mmHg for Diastolic BP (DBP). Additionally, compared to clinical invasive reference measurements, WeBPM’s SBP and DBP measurement errors are (–1.74 ± 4.9) mmHg and (0.37 ± 3.28) mmHg, respectively, further proving its outstanding performance. These results highlight WeBPM’s potential in personalized health management and remote monitoring, offering a new solution for continuous non-invasive BP monitoring.

Total 2