Zein, soy protein and whey protein can interact with lecithin to form composite systems. Proper application of ultrasonic, high-pressure homogenization and spray drying can make the composite systems more stable, expanding their application in delivery systems and making them promising for application in the fields of food, medicine, and other industries. This review focuses on the effect of the three physical field techniques on the interactions of the three proteins with lecithin and their application to deliver bioactive substances and drugs. We believe that this review will provide a basis for improving the stability of protein-lecithin composite systems and its application in delivery systems.

The gut microbiota and it’s metabolism are vital targets of probiotics regulating high fat-diet (HFD) induced hyperlipidemia, which can relieve the pressure caused by the striking growth of sub-health people. Pediococcus pentosaceus PP04 (PP04) could colonize in intestine to regulate gut microbiota and it’s metabolites directly, the rebalanced intestinal flora mediated by PP04 could facilitate the secretion of short chain fatty acids to control body weight gain, PP04 intervention also changed bile acid (BA) profiles and enhanced the ileal concentrations of antagonists including tauro-α/β-muricholic acid sodium salt and ursodeoxycholic acid to inhibit intestinal farnesoid X receptor/fibroblast growth factor 15 (FXR/FGF15) signaling coupled with the activation of hepatic FXR/small heterodimer partners signaling, which accelerated the hepatic BA de novo synthesis and excretion with feces to eliminate HFD caused hyperlipemia effectively. This study provided important evidence regarding PP04 as dietary supplement to relieve hyperlipidemia by influencing BA enterohepatic circulation.