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Open Access Clinical Research Issue
A case of bilateral vertebral artery dissecting aneurysms presenting with subarachnoid hemorrhage evaluated using computational fluid dynamics: Which is the rupture side?
Brain Hemorrhages 2025, 6(1): 57-60
Published: 24 April 2024
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Background

Saccular aneurysms (SAs) have been long studied in hemodynamics using computational fluid dynamics (CFD), while dissecting aneurysms (DAs) remain unclear. To estimate which side of the aneurysm ruptured, we evaluated the hemodynamics of the bilateral vertebral artery DAs (VADAs).

Case presentation

A 44-year-old male was diagnosed with subarachnoid hemorrhage by the rupture of either side of bilateral VADAs. The rupture side could not be determined on admission (Day 0). CFD was performed using a patient-specific geometry model obtained from 3-demensional (3D) rotational angiography (RA) on day 1. We predicted that the right DA had ruptured based on the hemodynamics, associated with flow stagnation and complexity in the ruptured SAs by a transient analysis with the patient-specific blood flow velocity waveforms. After careful observation, gadolinium-enhanced MRI on day 16 showed a contrast effect in the right wall and a change in the right shape was confirmed on the second 3D RA on day 17. According to both imaging evaluations and CFD, the right was presumed to be ruptured, and a flow-diverter stent was placed at the right VA. The right VADA did not re-rupture for 12 months.

Conclusion

Our results indicated that hemodynamics of ruptured DAs would be similar to that of ruptured SAs.

Open Access Case Report Issue
Computational fluid dynamics using dual-layer porous media modeling to evaluate the hemodynamics of cerebral aneurysm treated with FRED: A technical note
Brain Hemorrhages 2023, 4(1): 39-43
Published: 26 May 2022
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Flow diverter (FD) implantation is increasingly performed for aneurysms that are difficult to treat with conventional endovascular therapy and direct surgery. Now, a new FD stent, the Flow-Redirection Endoluminal Device (FRED), enters into clinical practice and is expected to have higher therapeutic efficacy. To predict whether an aneurysm is completely occluded by FRED, we have developed a novel computational fluid dynamics (CFD) technique using dual-layer porous media modeling that simulates its characteristic stent strut. This technique may be useful to evaluate hemodynamic changes in an aneurysm after FRED implantation using the preoperative patient-specific aneurysm geometry. The authors describe the novel CFD technique with a dual-layer porous media and report the potential usefulness of the technique to predict the aneurysm-occlusion status after FRED implantation preoperatively using an illustrative case of an unruptured internal carotid artery anterior wall aneurysm.

Open Access Short Communication Issue
Double porous media modeling in computational fluid dynamics for hemodynamics of stent-assisted coiling of intracranial aneurysms: A technical case report
Brain Hemorrhages 2020, 1(1): 85-88
Published: 18 February 2020
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Endovascular therapy is developing, but not all aneurysms are completely obliterated even by using the techniques such as stent-assisted coiling or a flow diverter. To predict the aneurysm-occlusion status after stent-assisted coiling, the authors applied computational fluid dynamics (CFD) using porous media modeling to propose a new technique with the double porous media settings, one of which is a porous media setting for a coiled aneurysm and another of which is that for an intracranial stent. CFD with double porous media settings using preoperative aneurysm geometry may be useful for simulating the hemodynamic changes in intracranial aneurysms after stent-assisted coiling.

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