Dynamically modulating the level of reactive oxygen species (ROS) presents a promising strategy for infected wound healing therapy, but conventional approaches predominantly focus on ROS generation, often neglecting the necessity of redox balance. Here we develop a pH-responsive bifunctional nanozyme through coupling sub-nanoscale 12-phosphotungstic acid (PTA) cluster with Fe₃O₄ nanoparticles. This Fe₃O₄-PTA (FPTA) nanozyme can dynamically regulate redox activity within the wound microenvironment: during the early bacterial infection phase of wound niche within acidic pH, it catalyzes the conversion of exogenous H₂O₂ into highly reactive oxygen species, inducing bacterial membrane disruption and apoptosis; while upon restoration of physiological pH during healing phase, it scavenges excess ROS, mitigates inflammation, and promotes re-epithelialization. Catalytic kinetics, evaluated through a double-fitting Michaelis–Menten model, reveals high intrinsic V_max values for H₂O₂ and TMB substrates, and the FPTA nanozyme exhibited potent scavenging capability against ABTS^•, ·OH, and H₂O₂, substantiating its bifunctional catalytic nature. In vitro and in vivo studies demonstrated excellent antibacterial efficacy, biocompatibility, accelerated re-epithelialization, and promoted the infected wound healing, highlighting Fe₃O₄-PTA as an effective bifunctional nanozyme for precise redox modulation in wound care.

Metal-organic frameworks (MOFs) have emerged as exceptional materials for atmospheric water harvesting (AWH) due to their superior adsorption properties in low humidity conditions (≤ 20% RH), but most MOF adsorbents typically exist in powder form, thus their aggregation induces significant transfer resistance to limit their adsorption kinetics and practical application potential. Here we prepared an organic-inorganic MOF-303@poly(acrylates) composite by in-situ growing MOF-303 within porous poly(acrylates) spheres. Our results demonstrate that the 87% loading of MOF-303@poly(acrylates) exhibits uniformly dispersed crystals with a crystal size that is 40% smaller compared to pure MOF-303 powder, while maintaining a water vapor adsorption capacity of 0.348 g·g⁻¹ at 20% RH and 298 K, which is comparable to that of an equivalent mass of the pure MOF-303 powder. In the dynamic water vapor test with a constant flow rate (50 mL·min⁻¹), the adsorption and desorption rates of the composite are 2.74 and 2 times faster than those of MOF-303 powder. After 100 consecutive adsorption and desorption cycles at 1780 mL·min⁻¹ (0.95 m·s⁻¹, light air), the water vapor adsorption capacity showed no significant decline. This composite strategy not only enhances adsorption kinetics but also advances MOF-based AWH systems for engineering applications.

In₂O₃ is an effective electrocatalyst to convert CO₂ to formic acid (HCOOH), but its inherent poor electrical conductivity limits the efficient charge transfer during the reaction. Additionally, the tendency of In₂O₃ particles to agglomerate during synthesis further limits the exposure of active sites. Here we address these issues by leveraging the template effect of graphene oxide and employing InBDC as a self-sacrificing template for the pyrolysis synthesis of In₂O₃@C. The resulting In₂O₃@C/rGO-600 material features In₂O₃@C nanocubes uniformly anchored on a support of reduced graphene oxide (rGO), significantly enhancing the active sites exposure. The conductive rGO network facilitates charge transfer during electrocatalysis, and the presence of oxygen vacancies generated during pyrolysis, combined with the strong electron-donating ability of rGO, enhances the adsorption and activation of CO₂. In performance evaluation, In₂O₃@C/rGO-600 exhibits a remarkable HCOOH Faradaic efficiency exceeding 94.0% over a broad potential window of −0.7 to −1.0 V (vs. reversible hydrogen electrode (RHE)), with the highest value of 97.9% at −0.9 V (vs. RHE) in a H-cell. Moreover, the material demonstrates an excellent cathodic energy efficiency of 71.6% at −0.7 V (vs. RHE). The study underscores the efficacy of uniformly anchoring metal oxide nanoparticles onto rGO for enhancing the electrocatalytic CO₂ reduction performance of materials.

Supported Pd catalysts show superior activities for olefin productions from alkynes through semi-hydrogenation reactions, but over-hydrogenation into alkanes highly decreases olefin selectivity. Using phenylacetylene semi-hydrogenation as a model reaction, here we explore the optimization approaches toward better Pd catalysts for alkyne semi-hydrogenation through investigating support effect and metal–support interactions. The results show that the states of Pd with supports can be tuned by varying oxide reducibility, loading ratios, and post-treatments. In our system, 0.06 wt.% Pd on rutile-TiO₂ nanorods shows the highest activity owing to the synergistic effects of single-atoms and clusters. Support reducibility can change the filling degrees of Pd 4d orbitals through varying interfacial bonding strengths, which further affect catalytic activity and selectivity.