This report summarizes the reservoir characterization [Wang et al., J. Hydrol., 2022] and multiphase flow property [Kou et al., J. Hydrol., 2021] in a target deep saline aquifer, upper Minnelusa sandstone in Wyoming. Multiscale petrophysical characterization and flow unit classification were carried out to identify two different facies groups: cross-bedded and massive sandstone. Based on the rock typing results, two representative core samples were selected accordingly to conduct coreflooding experiments. Results illustrate that the sub-core scale heterogeneity significantly affects CO₂-brine multiphase flow properties. As a result, the sub-core scale heterogeneity should be considered during CO₂ injection to reduce the uncertainties in storage and fluid flow.