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Review | Publishing Language: Chinese | Open Access

Research Progress on the Preparation, Structural Analysis and Physiological Functions of Glutamine Peptides

Lulu LIN Liping ZHENGGanlu MENGWenying LIULiang CHEN ( )Xinxue ZHANG ( )
Beijing Engineering Research Center of Protein and Functional Peptides, China National Research Institute of Food & Fermentation Industries Co., Ltd., Beijing 100015, China
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Abstract

Glutamine peptides (Gln peptides) refer to bioactive peptides containing glutamine (Gln) monomers at the non-N-terminus. Gln peptides are mainly derived from wheat proteins, corn proteins and other plant proteins, with strong stability, easy digestion and a variety of biological activities. In recent years, the development and application of Gln peptides have attracted the attention of researchers at home and abroad. In this article, the preparation methods and structure analysis of Gln peptides are reviewed, with the aim of providing new ideas for the development of bioactive peptides with characteristic structures. In addition, this article summarizes the biological activities of Gln peptides such as protecting intestinal activity, alleviating depression, antioxidant, anti-fatigue and immunomodulatory effects in order to provide a new perspective for promoting human nutritional health and related disease intervention. Finally, this article concludes with an outlook on the future application prospects of Gln peptides in the food field, aiming to provide a theoretical reference for improving the nutritional value and enhancing the health benefits of Gln peptides.

CLC number: TS201.4 Document code: A Article ID: 1002-6630(2025)14-0387-11

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Food Science
Pages 387-397

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Cite this article:
LIN L, ZHENG L, MENG G, et al. Research Progress on the Preparation, Structural Analysis and Physiological Functions of Glutamine Peptides. Food Science, 2025, 46(14): 387-397. https://doi.org/10.7506/spkx1002-6630-20241118-137

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Received: 18 November 2024
Published: 25 July 2025
© Beijing Academy of Food Sciences 2025.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).