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Review | Publishing Language: Chinese | Open Access

Recent Progress in the Application of Organoid Technology in the Field of Health Foods

Shaoshi ZHANG1,2 Jian ZHAO1,2Yu GUO1,2Wenjie YAN1,2 ( )
Beijing Key Laboratory of Bioactive Substances and Functional Food, College of Biochemical Engineering, Beijing Union University, Beijing 100023, China
Functional Testing Center of Health Food, College of Applied Arts and Science, Beijing Union University, Beijing 100191, China
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Abstract

With the continuous improvement of the evaluation system for health food technology, the existing evaluation methods are no longer able to meet the needs of future development. Therefore, it is particularly important to develop a more comprehensive and accurate evaluation system that combines advanced technological means with traditional evaluation models. Organoid technology, as a new biological means, can simulate the structure and function of human organs more realistically, improve the accuracy and reliability of experiments, and reduce the need for animal experiments. This paper explores the potential application of 3D organoid technology in health food research from the perspectives of toxicological evaluation, the absorption and metabolism of functional factors, the research and development of health foods for special populations, and the development of new evaluation models for functionalities. It also puts forward new considerations on the development direction of health food evaluation system. The aim is to provide a more accurate and physiologically relevant technical platform for the evaluation system of health foods, so as to promote the scientific research and development and strict supervision of health foods.

CLC number: TS218 Document code: A Article ID: 1002-6630(2025)14-0357-09

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Food Science
Pages 357-365

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Cite this article:
ZHANG S, ZHAO J, GUO Y, et al. Recent Progress in the Application of Organoid Technology in the Field of Health Foods. Food Science, 2025, 46(14): 357-365. https://doi.org/10.7506/spkx1002-6630-20241010-047

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Received: 10 October 2024
Published: 25 July 2025
© Beijing Academy of Food Sciences 2025.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).