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Review | Publishing Language: Chinese | Open Access

Research Progress in the Structure, Biological Function and Extraction of Bovine Lactoferrin

Zihan KONG1 Linfang ZHANG2Xiangchen MENG1Fei LIU1 ( )
College of Food Science, Northeast Agricultural University, Harbin 150030, China
Department of Grain Engineering, Heilongjiang Communications Polytechnic, Harbin 161002, China
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Abstract

Bovine lactoferrin (BLF), as an important iron-binding glycoprotein in mammalian milk, has a broad application prospect in the fields of food, medicine and nutraceuticals. This article briefly introduces the structural characteristics of BLF, and systematically summarizes its various biological functions including antibacterial, immunomodulatory, antioxidant, antiviral, antitumor and its mechanism of action. Meanwhile, it reviews the techniques currently used to extract BLF with special reference to their advantages and disadvantages. Finally, the current research hotspots and prospects of BLF are analyzed. This review provides a theoretical reference for the in-depth understanding of the biological properties of BLF and for its industrial development, thereby advancing its application in functional foods and foods for special medical purposes

CLC number: TS252.1 Document code: A Article ID: 1671-5187(2025)04-0062-08

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Journal of Dairy Science and Technology
Pages 62-69

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Cite this article:
KONG Z, ZHANG L, MENG X, et al. Research Progress in the Structure, Biological Function and Extraction of Bovine Lactoferrin. Journal of Dairy Science and Technology, 2025, 48(4): 62-69. https://doi.org/10.7506/rykxyjs1671-5187-20250313-019

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Received: 13 March 2025
Published: 01 July 2025
© Bright Dairy & Food Co., Ltd. 2025.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).