AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
PDF (709.6 KB)
Collect
Submit Manuscript AI Chat Paper
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Research Article | Open Access

The impact of Lévy jumps on the dynamics of an HBV model with immune interaction and intracellular transmission pathways

Faria Mirza1,2, Ziyad A. Alhussain3( ), Jun Feng1,2( ), Anwarud Din4
School of Mathematical Sciences, Chengdu University of Technology, Chengdu, 610059, PR China
Geomathematics Key Laboratory of Sichuan Province, Chengdu University of Technology, Chengdu, 610059, PR China
Department of Statistics and Operations Research, College of Science, Qassim University, Buraydah, 52373, Saudi Arabia
School of Mechanical and Electrical Engineering, Chengdu University of Technology, Chengdu, 610059, PR China
Show Author Information

Abstract

This work develops a stochastic model to explore the dynamical behaviour of hepatitis B virus (HBV) infection by incorporating virus-to-cell transmission, cell-to-cell transmission, and the cytotoxic T lymphocyte (CTL) immune response under Lévy noise, which represents sudden environmental perturbations. The model is formulated, and its feasibility is investigated. The study is further enriched by proving the uniqueness, existence, and positivity of the global solution. A sufficient extinction condition is derived by using a combined infected-virus Lyapunov functional. In addition, a conditional sufficient criterion for long-term average persistence is established under bounded-state dynamics. The extinction result shows that infected hepatocytes and free virus particles vanish when the corresponding sufficient extinction condition is satisfied, whereas persistence is obtained under the boundedness assumption on the normalization factor and the condition Δ P > 0. At the end, numerical simulations are performed to validate and illustrate the analytical findings. Additional numerical reliability tests, including step-size sensitivity, relative error estimation, positivity verification, and comparison with a positivity-preserving truncated Euler-Maruyama scheme, are also provided. The results demonstrate that stochastic environmental perturbations can significantly affect the transmission of infectious diseases, including HBV. Significantly, excessive noise levels can greatly restrict a population's ability to spread the disease.

CLC number: 60G51, 60H10, 65C30, 68T07, 92D30

References

【1】
【1】
 
 
AIMS Mathematics
Pages 21036-21068

{{item.num}}

Comments on this article

Go to comment

< Back to all reports

Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

Review Comment

Close
Close
Cite this article:
Mirza F, Alhussain ZA, Feng J, et al. The impact of Lévy jumps on the dynamics of an HBV model with immune interaction and intracellular transmission pathways. AIMS Mathematics, 2026, 11(7): 21036-21068. https://doi.org/10.3934/math.2026854

2

Views

0

Downloads

0

Crossref

0

Web of Science

0

Scopus

Received: 07 May 2026
Accepted: 04 July 2026
Published: 15 July 2026
©2026 the Author(s), licensee AIMS Press.

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0)