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Review | Open Access

Dental implant surface modification for promoting peri-implant osseointegration in osteoporosis

Boyu Liu1,2Xiaojie Chen1,2Shangyong Zuo3Yihong Chen1,2Hengrong Xiong1,2Zhiwei Peng3Ousheng Liu1,2( )Qian Peng1,2( )
Xiangya Stomatological Hospital and Xiangya School of Stomatology, Central South University, Changsha, 410008, China
Hunan Key Laboratory of Oral Health Research, Central South University, Changsha, 410008, China
School of Minerals Processing and Bioengineering, Central South University, Changsha, 410083, China
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Abstract

Osteoporosis (OP) is a metabolic disease characterized by reduced bone mass, decreased bone mineral density, and increased bone fragility. This not only makes patients prone to fractures but also renders the bone tissues in the oral cavity vulnerable to damage, leading to premature loosening and loss of teeth. Implant prosthodontics is currently the best approach for managing partial and complete edentulism. When implants are placed in the oral cavity of OP patients, there is a delay in osseointegration and insufficient primary stability of dental implants, which affects the success rate of implantation. Ensuring their quick and firm integration with the bone tissue in the body of OP patients is a pressing issue that needs to be addressed in the field of oral implant prosthetics. This paper reviews commonly used methods of implant surface modification, such as physical, chemical, and biological modifications, and discusses the advantages of these technologies and the mechanisms of anti-OP effects, aiming at improving osseointegration of implants in OP patients, shortening the healing period, and enhancing the success rate of implantation. This will be significant for the research and development of new implants and for expanding the clinical indications of implant prosthodontics.

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Oral Science and Homeostatic Medicine
Article number: 9610023

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Cite this article:
Liu B, Chen X, Zuo S, et al. Dental implant surface modification for promoting peri-implant osseointegration in osteoporosis. Oral Science and Homeostatic Medicine, 2025, 1(2): 9610023. https://doi.org/10.26599/OSHM.2025.9610023

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Received: 10 May 2025
Revised: 03 July 2025
Accepted: 10 July 2025
Published: 31 July 2025
© The Author(s) 2025. Published by Tsinghua University Press.

This article is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the original author(s) and the source, provide a link to the license, and indicate if changes were made. See https://creativecommons.org/licenses/by/4.0/