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In this research, the preparation of licorice extract and the biosynthesis of manganese oxide in the treatment of stomach cancer were investigated by examining the cytotoxicity of the stomach cancer line. The structural properties of manganese oxide were also studied through X-ray examination, scanning electron microscope (SEM), and infrared spectroscopy, where it was found that manganese oxide is polycrystalline, and the average grain size is 62.571 nm, but by SEM, the grain size is 93.49–47.74 nm.


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Effect of Licorice Extract and Manganese Oxide Biosynthesis in the Treatment of Stomach Cancer

Show Author's information Nadia Jasim Ghdeeb( )
Mustansyriah University, College of Science, Department of Physics, Baghdad, Iraq

Abstract

In this research, the preparation of licorice extract and the biosynthesis of manganese oxide in the treatment of stomach cancer were investigated by examining the cytotoxicity of the stomach cancer line. The structural properties of manganese oxide were also studied through X-ray examination, scanning electron microscope (SEM), and infrared spectroscopy, where it was found that manganese oxide is polycrystalline, and the average grain size is 62.571 nm, but by SEM, the grain size is 93.49–47.74 nm.

Keywords: structure, licorice extract, manganese dioxide nanoparticles (MnO2 NPs), anticancer.

References(20)

[1]
G. Schmid. Nanoparticles: From Theory to Applications, 2nd, Completely Revised and Updated Edition. Wiley-VCH, 2006.
[2]

C. Burda, X.B. Chen, R. Narayanan, et al. Chemistry and properties of nanocrystals of different shapes. Chemical Reviews, 2005, 105(4): 1025−1102. https://doi.org/10.1021/cr030063a

[3]

M.M. Najafpour, S.I. Allakhverdiev. Manganese compounds as water oxidizing catalysts for hydrogen production via water splitting: From manganese complexes to nano-sized manganese oxides. International Journal of Hydrogen Energy, 2012, 37(10): 8753−8764. https://doi.org/10.1016/j.ijhydene.2012.02.075

[4]

T. Lin, L. Yu, M. Sun, et al. Mesoporous α-MnO2 microspheres with high specific surface area: Controlled synthesis and catalytic activities. Chemical Engineering Journal, 2016, 286: 114−121. https://doi.org/10.1016/j.cej.2015.09.024

[5]

V. Štengl, D. Králová, F. Opluštil, et al. Mesoporous manganese oxide for warfare agents degradation. Microporous and Mesoporous Materials, 2012, 156: 224−232. https://doi.org/10.1016/j.micromeso.2012.02.031

[6]
M. Alavi, N. Karimi. Characterization, antibacterial, total antioxidant, scavenging, reducing power and ion chelating activities of green synthesized silver, copper and titanium dioxide nanoparticles using Artemisia haussknechtii leaf extract. Artificial Cells, Nanomedicine, and Biotechnology, 2018, 46(8): 2066–2081.
DOI
[7]
R. Ganguly, A.K. Singh, R. Kumar, et al. Nanoparticles as modulators of oxidative stress. In: Nanotechnology in Modern Animal Biotechnology. Amsterdam: Elsevier, 2019: 29–35.
DOI
[8]

Y. Anzabi. Biosynthesis of ZnO nanoparticles using barberry (Berberis vulgaris) extract and assessment of their physico-chemical properties and antibacterial activities. Green Processing and Synthesis, 2018, 7(2): 114−121. https://doi.org/10.1515/gps-2017-0014

[9]

N.J. Ghdeeb, N.A. Hussain. Antimicrobial activity of ZnO nanoparticles prepared using a green synthesis approach. Nano Biomedicine and Engineering, 2023, 15(1): 14−20. https://doi.org/10.26599/NBE.2023.9290003

[10]

R.L. Siegel, K.D. Miller, A. Jemal. Cancer statistics, 2016. CA:A Cancer Journal for Clinicians, 2016, 66(1): 7−30. https://doi.org/10.3322/caac.21332

[11]

R.L. Siegel, K.D. Miller, A. Jemal. Cancer statistics, 2019. CA:A Cancer Journal for Clinicians, 2019, 69(1): 7−34. https://doi.org/10.3322/caac.21551

[12]

S. Shukla, A. Mehta. Anticancer potential of medicinal plants and their phytochemicals: A review. Brazilian Journal of Botany, 2015, 38(2): 199−210. https://doi.org/10.1007/s40415-015-0135-0

[13]

A. Petruczynik, T. Tuzimski, T. Plech, et al. Comparison of anticancer activity and HPLC-DAD determination of selected isoquinoline alkaloids from Thalictrum foetidum, Berberis sp. and Chelidonium majus extracts. Molecules, 2019, 24(19): 3417. https://doi.org/10.3390/molecules24193417

[14]

T. Soejima, K. Nishizawa, R. Isoda. Monodisperse manganese oxide nanoparticles: Synthesis, characterization, and chemical reactivity. Journal of Colloid and Interface Science, 2018, 510: 272−279. https://doi.org/10.1016/j.jcis.2017.09.082

[15]

A. Lichota, K. Gwozdzinski. Anticancer activity of natural compounds from plant and marine environment. International Journal of Molecular Sciences, 2018, 19(11): 3533. https://doi.org/10.3390/ijms19113533

[16]

Huda NU, Ahmed M, Mushtaq N, et al. Kickxia elatine-assisted Bio-fabrication of Nano-silver and Their Antioxidant, Anti-alpha Amylase, and Anti-acetylcholinesterase Properties. Nano Biomedicine and Engineering, 2023, 15(2): 150−169. https://doi.org/10.26599/NBE.2023.9290021

[17]

Y.-Y. Ren, H. Yang, T. Wang, et al. Green synthesis and antimicrobial activity of monodisperse silver nanoparticles synthesized using Ginkgo Biloba leaf extract. Physics Letters A, 2016, 380(45): 3773−3777. https://doi.org/10.1016/j.physleta.2016.09.029

[18]

R. Dobrucka, J. Dlugaszewska, M. Kaczmarek. Cytotoxic and antimicrobial effects of biosynthesized ZnO nanoparticles using of Chelidonium majus extract. Biomedical Microdevices, 2017, 20: 5. https://doi.org/10.1007/s10544-017-0233-9

[19]
Huang, Y. J., Li, W. S. Preparation of Manganese dioxide for oxygen reduction in zinc air battery by hydro thermal method. Journal of Inorganic Materials, 2013, 28(3): 341–346.
DOI
[20]

D. Jaganyi, M. Altaf, I. Wekesa. Synthesis and characterization of whisker-shaped MnO2 nanostructure at room temperature. Applied Nanoscience, 2013, 3(4): 329−333. https://doi.org/10.1007/s13204-012-0135-3

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Publication history

Received: 20 July 2023
Revised: 10 September 2023
Accepted: 31 October 2023
Published: 12 January 2024
Issue date: June 2024

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© The Author(s) 2024.

Acknowledgements

Acknowledgements

I would like to thank everyone who helped me complete it.

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This is an open-access article distributed under  the  terms  of  the  Creative  Commons  Attribution  4.0 International  License (CC BY) (http://creativecommons.org/licenses/by/4.0/), which  permits  unrestricted  use,  distribution,  and reproduction in any medium, provided the original author and source are credited.

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