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Special Reports | Open Access

Clinical diagnosis guidelines and neurorestorative treatment for chronic disorders of consciousness (2021 China version)

Yusheng Li1( )Jianghong He2Bo Yang1Hui Zhang3Zhonghua Yang2Jianhui Fu4Lian Huang5Hong Chen6Xiaofeng Yang7Yijun Bao8
The 1st Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China
Tiantan Hospital, Capital Medical University, Beijing 100070, China
Zhengzhou Central Hospital, Zhengzhou 450007, Henan, China
Shanghai Huashan Hospital, Shanghai 200040, China
The First Affiliated Hospital of Ji’nan University, Guangzhou 510630, Guangdong, China
Tongji Hospital of Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, China
The Fourth Hospital of China Medical University, Shenyang 110084, Liaoning, China
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Abstract

Chronic disorders of consciousness (DOC) include the vegetative state and the minimally consciousness state. The DOC diagnosis mainly relies on the evaluation of clinical behavioral scales, electrophysiological testing, and neuroimaging examinations. No specifically effective neurorestorative methods for chronic DOC currently exist. Any valuable exploration therapies of being able to repair functions and/or structures in the consciousness loop (e.g., drugs, hyperbaric medicines, noninvasive neurostimulation, sensory and environmental stimulation, invasive neuromodulation therapy, and cell transplantation) may become effective neurorestorative strategies for chronic DOC. In the viewpoint of Neurorestoratology, this guideline proposes the diagnostic and neurorestorative therapeutic suggestions and future exploration direction for this disease following the review of the existing treatment exploration achievements for chronic DOC.

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Journal of Neurorestoratology
Pages 50-59
Cite this article:
Li Y, He J, Yang B, et al. Clinical diagnosis guidelines and neurorestorative treatment for chronic disorders of consciousness (2021 China version). Journal of Neurorestoratology, 2021, 9(1): 50-59. https://doi.org/10.26599/JNR.2021.9040006

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Received: 30 October 2020
Revised: 28 February 2021
Accepted: 10 March 2021
Published: 09 June 2021
© The authors 2021

This article is published with open access at http://jnr.tsinghuajournals.com

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