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Journal of Neurorestoratology 2021, 9(1): 50-59 https://doi.org/10.26599/JNR.2021.9040006
Special Reports | Open Access | Issue | Published: 09 June 2021

Clinical diagnosis guidelines and neurorestorative treatment for chronic disorders of consciousness (2021 China version)

Show Author's Information Yusheng Li1( ),  Jianghong He2,  Bo Yang1,  Hui Zhang3,  Zhonghua Yang2,  Jianhui Fu4,  Lian Huang5,  Hong Chen6,  Xiaofeng Yang7,  Yijun Bao8
The 1st Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China
Tiantan Hospital, Capital Medical University, Beijing 100070, China
Zhengzhou Central Hospital, Zhengzhou 450007, Henan, China
Shanghai Huashan Hospital, Shanghai 200040, China
The First Affiliated Hospital of Ji’nan University, Guangzhou 510630, Guangdong, China
Tongji Hospital of Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, China
The Fourth Hospital of China Medical University, Shenyang 110084, Liaoning, China
Keywords:
neurorestoration, clinical guideline, chronic disorders of consciousness
Cite this article:
Li Y, He J, Yang B, et al. Clinical diagnosis guidelines and neurorestorative treatment for chronic disorders of consciousness (2021 China version). Journal of Neurorestoratology, 2021, 9(1): 50-59. https://doi.org/10.26599/JNR.2021.9040006
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Abstract Full text About this article

Chronic disorders of consciousness (DOC) include the vegetative state and the minimally consciousness state. The DOC diagnosis mainly relies on the evaluation of clinical behavioral scales, electrophysiological testing, and neuroimaging examinations. No specifically effective neurorestorative methods for chronic DOC currently exist. Any valuable exploration therapies of being able to repair functions and/or structures in the consciousness loop (e.g., drugs, hyperbaric medicines, noninvasive neurostimulation, sensory and environmental stimulation, invasive neuromodulation therapy, and cell transplantation) may become effective neurorestorative strategies for chronic DOC. In the viewpoint of Neurorestoratology, this guideline proposes the diagnostic and neurorestorative therapeutic suggestions and future exploration direction for this disease following the review of the existing treatment exploration achievements for chronic DOC.


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About this article

Clinical diagnosis guidelines and neurorestorative treatment for chronic disorders of consciousness (2021 China version)

Show Author's information Yusheng Li1( ), Jianghong He2, Bo Yang1, Hui Zhang3, Zhonghua Yang2, Jianhui Fu4, Lian Huang5, Hong Chen6, Xiaofeng Yang7, Yijun Bao8
The 1st Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China
Tiantan Hospital, Capital Medical University, Beijing 100070, China
Zhengzhou Central Hospital, Zhengzhou 450007, Henan, China
Shanghai Huashan Hospital, Shanghai 200040, China
The First Affiliated Hospital of Ji’nan University, Guangzhou 510630, Guangdong, China
Tongji Hospital of Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang, China
The Fourth Hospital of China Medical University, Shenyang 110084, Liaoning, China

Abstract

Chronic disorders of consciousness (DOC) include the vegetative state and the minimally consciousness state. The DOC diagnosis mainly relies on the evaluation of clinical behavioral scales, electrophysiological testing, and neuroimaging examinations. No specifically effective neurorestorative methods for chronic DOC currently exist. Any valuable exploration therapies of being able to repair functions and/or structures in the consciousness loop (e.g., drugs, hyperbaric medicines, noninvasive neurostimulation, sensory and environmental stimulation, invasive neuromodulation therapy, and cell transplantation) may become effective neurorestorative strategies for chronic DOC. In the viewpoint of Neurorestoratology, this guideline proposes the diagnostic and neurorestorative therapeutic suggestions and future exploration direction for this disease following the review of the existing treatment exploration achievements for chronic DOC.

Keywords: neurorestoration, clinical guideline, chronic disorders of consciousness

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Received: 30 October 2020
Revised: 28 February 2021
Accepted: 10 March 2021
Published: 09 June 2021
Issue date: March 2021

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© The authors 2021

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