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Review Article | Open Access | Online First

Research progress and application of food and medicine homology plants in the treatment of functional gastrointestinal disorders

Xue-Ying Xu1, Shu-Jing Zhang2,3, Chu-Chu Hu2, Yi Wang1,2,3, Yu Tang1,2( ), Ying-Chao Wang1,2( )
Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University, Hangzhou 310018, China
Jinan Microecological Biomedicine Shandong Laboratory, Jinan 250118, China
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Highlights

(1) Promote the industrialization of medicine and food homology herbs by combining market product information.

(2) Safety and health claims for medicine and food homology herbs.

(3) By analyzing the extracts, ingredients, and formulas, providing inspiration and a basis for the development and utilization of medicine and food homologous products.

Abstract

Functional gastrointestinal disorders (FGIDs) are a group of digestive disorders affecting nearly 40% of the global population. In recent years, studies have demonstrated the significant therapeutic effects of a wealth of herbal medicines and their bioactive components in the treatment of FGIDs. Notably, among these herbal preparations, food and medicine homology (FMH) plants account for a significant portion. This review focuses on the use of FMH plants and FMH-containing formulas for the treatment of FGIDs, provides an overview of their pharmacological effects, and analyzes the modeling and efficacy of those formulas, FMH extracts, and corresponding components in the treatment of gastrointestinal disorders. This review aims to serve as a reference for the research and application of FMH used to treat FGIDs.

Graphical Abstract

Food and medicine homologous materials have potential advantages in the treatment of chronic diseases such as functional gastrointestinal disorders. Many clinical reports show that traditional Chinese herbs have certain therapeutic effects, laying a foundation for the development of new products.

Keywords

functional gastrointestinal disorders (FGIDs)food and medicine homologyTCM formulasChinese medicine

References

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Food & Medicine Homology
DOI: 10.26599/FMH.2027.9420148

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Cite this article:
Xu X-Y, Zhang S-J, Hu C-C, et al. Research progress and application of food and medicine homology plants in the treatment of functional gastrointestinal disorders. Food & Medicine Homology, 2026, https://doi.org/10.26599/FMH.2027.9420148

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Web of Science
Received: 09 August 2024
Revised: 22 September 2024
Accepted: 05 October 2024
Published: 22 May 2026
© National R & D Center for Edible Fungus Processing Technology 2026. Published by Tsinghua University Press.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).