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Review Article | Open Access

Research Progress on the Application of Irreversible Electroporation Ablation in Cancers

Rong ZhangLiting XieQijing JinChengyue ZhangTeng GuoQiyu Zhao( )Tian’an Jiang ( )
Department of Ultrasound Medicine, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China
Department of Ultrasound Medicine, Affiliated Jinhua Hospital Zhejiang University School of Medicine, Jinhua, Zhejiang, P.R. China
Key Laboratory of Pulsed Power Translational Medicine of Zhejiang Province, Hangzhou, Zhejiang, P.R. China
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Abstract

Irreversible electroporation (IRE) is an innovative non-thermal ablation technique increasingly utilized in cancer treatment due to its unique operational principles and clinical advantages. As a novel interventional ultrasound technology, IRE has undergone extensive research, development, and practical application over the years. IRE ablation, particularly in conjunction with immunotherapy, has emerged as a significant modality in cancer treatment and related fields. This article aims to present the advancements in irreversible electroporation ablation for cancer through an examination of both basic research and clinical applications.

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Advanced Ultrasound in Diagnosis and Therapy
Pages 229-244

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Cite this article:
Zhang R, Xie L, Jin Q, et al. Research Progress on the Application of Irreversible Electroporation Ablation in Cancers. Advanced Ultrasound in Diagnosis and Therapy, 2025, 9(3): 229-244. https://doi.org/10.26599/AUDT.2025.240052

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Received: 27 September 2024
Revised: 14 December 2024
Accepted: 19 March 2025
Published: 01 September 2025
2576-2508/© AUDT 2025

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed