Olfactory ensheathing cell transplantation for a patient with chronic sciatic nerve injury

Feng Zhang; Xiangzhi Meng; Fang Lu; Aixian Liu; Hongyun Huang

doi:10.2147/JN.S120524

Journal of Neurorestoratology 2017, 5(1): 1-4 https://doi.org/10.2147/JN.S120524

Case Report |

Open Access | Issue | Published: 28 December 2017

Olfactory ensheathing cell transplantation for a patient with chronic sciatic nerve injury

Show Author's Information Hide Author's Information Feng Zhang^{¹^,²}, Xiangzhi Meng^², Fang Lu^², Aixian Liu^², Hongyun Huang^{¹^,²}(

)

1Cell Therapy Center, Beijing Hongtianji Neuroscience Academy,

2Neurorehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, People’s Republic of China

Keywords:

neurorestoration, olfactory ensheathing cell transplantation, peripheral nerve injury, sciatic nerve injury, function improvement

Cite this article:

Zhang F, Meng X, Lu F, et al. Olfactory ensheathing cell transplantation for a patient with chronic sciatic nerve injury. Journal of Neurorestoratology, 2017, 5(1): 1-4. https://doi.org/10.2147/JN.S120524

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Abstract Full text About this article

Abstract

Objective:

To observe the result of olfactory ensheathing cell (OEC) transplantation in a patient with chronic sciatic nerve injury.

Case report:

A 53-year-old male patient with chronic (1 year) sciatic nerve injury on left side received OEC transplantation at the lesion site. He received follow-up assessment according to the American Spinal Injury Association standard at 10 days, 6 months, and 1 year after OEC therapy. The muscle strength of his left lower limb increased and numbness decreased during the early stage of cell therapy. His motor function improved with each evaluation. His limp walking gait recovered, and numbness sensation got nearly normal after 1 year of follow-up. There were no side effects.

Conclusion:

OEC transplantation may be an option for chronic peripheral (sciatic) nerve injury.

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Abstract

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About this article

Olfactory ensheathing cell transplantation for a patient with chronic sciatic nerve injury

Show Author's information Hide Author's Information Feng Zhang^{¹^,²}, Xiangzhi Meng^², Fang Lu^², Aixian Liu^², Hongyun Huang^{¹^,²}(

)

1Cell Therapy Center, Beijing Hongtianji Neuroscience Academy,

2Neurorehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, People’s Republic of China

Abstract

Objective:

To observe the result of olfactory ensheathing cell (OEC) transplantation in a patient with chronic sciatic nerve injury.

Case report:

Conclusion:

OEC transplantation may be an option for chronic peripheral (sciatic) nerve injury.

Keywords: neurorestoration, olfactory ensheathing cell transplantation, peripheral nerve injury, sciatic nerve injury, function improvement

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Published: 28 December 2017

Issue date: December 2017

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