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Review

Preparation and Applications of Micro-Nano Bioactive Glass

Zhengyu YANG1,2,3Fujian ZHAO4Chang DU1,2,3Xiaofeng CHEN1,2,3( )
Department of Biomaterials, School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China
National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou 510006, China
Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education, South China University of Technology, Guangzhou 510006, China
Stomatological Hospital, Southern Medical University, Guangzhou 510280, China
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Abstract

Micro-nano bioactive glass (MNBG) has a good biological activity and is widely used in tissue engineering. In recent years, a variety of metal ions are incorporated into the network structure of materials during the preparation of MNBG, thereby endowing MNBG with various physicochemical and biological functional properties. However, the exact mechanism of interaction between the ion release products of MNBG and human cells is not fully clarified. This review represented the preparation methods and processes of MNBG and the application of its lysates in bone and tooth and other hard tissue repair, skin tissue repair, cancer treatment and cell imaging. This review could provide a reference for the further development of MNBGs applied to the biomedical field.

CLC number: R318.08 Document code: A Article ID: 0454-5648(2023)10-2553-13

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Journal of the Chinese Ceramic Society
Pages 2553-2565

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Cite this article:
YANG Z, ZHAO F, DU C, et al. Preparation and Applications of Micro-Nano Bioactive Glass. Journal of the Chinese Ceramic Society, 2023, 51(10): 2553-2565. https://doi.org/10.14062/j.issn.0454-5648.20230200

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Received: 31 March 2023
Revised: 09 June 2023
Published: 04 August 2023
© 2023 Journal of the Chinese Ceramic Society