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Publishing Language: Chinese | Open Access

Evaluation of the effect of concentrated growth factor in guided bone regeneration in maxillary anterior tooth defects

Yamin WANG1, Zhen ZHOU2( ), Junfeng DAO3, Qiyue CHEN4, Wenjing LIU3, Guangbao SONG5
Department of Periodontal Disease, Stomatological Hospital, Southern Medical University, Guangzhou 510280, China
Implant Center, Stomatological Hospital, Southern Medical University, Guangzhou 510280, China
Department of Prosthodontics, Stomatological Hospital, Southern Medical University, Guangzhou 510280, China
Department of Dental Pulp, Haizhu Hospital, Stomatological Hospital, Southern Medical University,Guangzhou 510280, China
Stomatology, Southern Medical University Special Diagnosis Center, Guangzhou 510280, China
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Abstract

Objective

To investigate the clinical effect of concentrated growth factor (CGF) applied in guided bone regeneration (GBR) for severe bone deficiency in the anterior maxilla.

Methods

Forty patients with bone defects in the anterior maxilla were chosen to be treated with GBR, 20 patients were treated with CGF applied in GBR as the observation group, and the other 20 patients were treated only with GBR as the control group. The evaluation of wound healing was performed after the operation, and bone augmentation was evaluated half a year after the operation.

Results

The first-stage healing rate of soft tissue wounds in the observation group was 100% and 75% in the control group, and the primary healing rate in the observation group was better than that in the control group (P = 0.017). The changes in bone width of the observation group were (3.70 ± 0.28) mm, and those of the control group were (2.96 ± 0.16) mm. The bone augmentation in the observation group was higher than that in the control group (P = 0.000).

Conclusion

CGF applied in GBR has a good effect on bone augmentation for severe bone deficiency in the anterior maxilla.

Keywords

concentrated growth factortooth lossanterior teethbone defectbone incrementguided bone regenerationdental implantmaxillawound healing
CLC number: R78 Document code: A Article ID: 2096-1456(2020)04-0236-05

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Journal of Prevention and Treatment for Stomatological Diseases
Volume 28 Issue 4,
April 2020
Pages 236-240
DOI: 10.12016/j.issn.2096-1456.2020.04.006

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Cite this article:
WANG Y, ZHOU Z, DAO J, et al. Evaluation of the effect of concentrated growth factor in guided bone regeneration in maxillary anterior tooth defects. Journal of Prevention and Treatment for Stomatological Diseases, 2020, 28(4): 236-240. https://doi.org/10.12016/j.issn.2096-1456.2020.04.006

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Received: 16 April 2019
Revised: 18 July 2019
Published: 20 April 2020
© 2020 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases

This article is licensed under a Creative Commons Attribution 4.0 International License.