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Review Article | Publishing Language: Chinese | Open Access

A multiomics approach to study the associations between microbial communities and functions and dental caries

Yuanyuan HUO, Xuan HAN, Yuqing LI, Jing ZOU( )
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
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Abstract

The pathogenic mechanisms by which oral microbial communities affect the occurrence and development of dental caries remain unclear. Applications that make use of high-through put sequencing technologies and metaomics approaches to research dental caries etiology can provide new ideas about disease prevention and treatment. In this article, we review advanced research presented in metaomics studies, including genomic, metagenomic, metatranscriptomic, metaproteomic and metabolomics studies of dental caries.

Keywords

Dental cariesOral microbial communityMicro-ecologyMetagenomicsMetatranscriptomicsMetaproteomicsMetabolomics
CLC number: R781 Document code: A Article ID: 2096-1456(2018)03-0195-05

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Journal of Prevention and Treatment for Stomatological Diseases
Volume 26 Issue 3,
March 2018
Pages 195-199
DOI: 10.12016/j.issn.2096-1456.2018.03.011

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Cite this article:
HUO Y, HAN X, LI Y, et al. A multiomics approach to study the associations between microbial communities and functions and dental caries. Journal of Prevention and Treatment for Stomatological Diseases, 2018, 26(3): 195-199. https://doi.org/10.12016/j.issn.2096-1456.2018.03.011

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Received: 27 April 2017
Revised: 24 August 2017
Published: 20 March 2018
© 2018 by Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases

This article is licensed under a Creative Commons Attribution 4.0 International License.