Visual analysis of mesenchymal stem cell research in liver disease based on bibliometrics

Chengzuo Han; Rui Wang; Nan Xu; Xuyong Wei; Qiang Wei; Xiao Xu

doi:10.1016/j.iliver.2022.11.006

iLIVER 2022, 1(4): 283-291 https://doi.org/10.1016/j.iliver.2022.11.006

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Open Access | Issue | Published: 23 November 2022

Visual analysis of mesenchymal stem cell research in liver disease based on bibliometrics

Show Author's Information Hide Author's Information Chengzuo Han^{^a^,^b^,¹}, Rui Wang^{^a^,^b^,¹}, Nan Xu^{^a^,^b}, Xuyong Wei^{^a^,^b}, Qiang Wei^{^a^,^b}(

), Xiao Xu^{^a^,^b}

(

)

Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China

Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, 310024, China

¹ These authors contributed equally to this work.

Keywords:

Visualization, Mesenchymal stem cells, Bibliometrics, Liver disease

Cite this article:

Han C, Wang R, Xu N, et al. Visual analysis of mesenchymal stem cell research in liver disease based on bibliometrics. iLIVER, 2022, 1(4): 283-291. https://doi.org/10.1016/j.iliver.2022.11.006

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Abstract

The research of mesenchymal stem cells (MSCs) in the field of liver diseases has received more and more attention. This paper introduces the current situation, hot spots, and development trends in this field. Comprehensive searches were conducted using Web of Science Core Collection from January 1, 2000 to December 13, 2021 with the following keywords: TS(topic) = (liver^*OR hepatic^*OR hepatocyte) AND TS(topic) = (Mesenchymal stem cell^*). VOSviewer (version 1.6.16) and CiteSpace V are used as bibliometric tools to analyze and visualize the knowledge graph. A total of 4452 papers were included in this study, and the number of research papers on MSCs in the field of liver diseases increased from January 2000 to December 2020. Eighty-four countries and regions have published articles on research in this field, among which China and the United States are the main two countries of publication. Based on the keyword burst detection, we find that the research in this field has shifted from basic research to clinical application, from medical research to interdisciplinary research. Tissue engineering and regenerative medicine are the frontier fields of MSCs research in liver diseases. Multicountry, multi-author cooperation, and multi-disciplinary intersection are the research trends in this field. Exocrine body, obesity, and tissue engineering are the hotspots in this field.

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About this article

Visual analysis of mesenchymal stem cell research in liver disease based on bibliometrics

Show Author's information Hide Author's Information Chengzuo Han^{^a^,^b^,¹}, Rui Wang^{^a^,^b^,¹}, Nan Xu^{^a^,^b}, Xuyong Wei^{^a^,^b}, Qiang Wei^{^a^,^b}(

), Xiao Xu^{^a^,^b}

(

)

Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, 310024, China

¹ These authors contributed equally to this work.

Abstract

Keywords: Visualization, Mesenchymal stem cells, Bibliometrics, Liver disease

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Publication history

Received: 31 August 2022

Revised: 10 November 2022

Accepted: 11 November 2022

Published: 23 November 2022

Issue date: December 2022

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This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).