Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors

De-Ping Wang; Fang-Ying Jiang; Xian-Yan Zeng; Yu-Jie Liu; Rong Zhao; Mei-Yue Wang; Jing Luo; Chen Chen; Yong Zhu; Ji-Min Cao

doi:10.1016/j.gendis.2022.07.001

Genes & Diseases 2023, 10(2): 389-392 https://doi.org/10.1016/j.gendis.2022.07.001

Rapid Communication |

Open Access | Issue | Published: 31 July 2022

Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors

Show Author's Information Hide Author's Information De-Ping Wang^{^a^,¹}, Fang-Ying Jiang^{^a^,¹}, Xian-Yan Zeng^{^b^,¹}, Yu-Jie Liu^{^c^,}, Rong Zhao^{^a}, Mei-Yue Wang^{^a}, Jing Luo^{^d}, Chen Chen^{^c}(

), Yong Zhu^{^b}(

), Ji-Min Cao^{^a}(

)

Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, And the Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi 030001, China

College of Life Sciences, Chongqing Medical University, Chongqing 400016, China

Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China

Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China

¹ These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

Cite this article:

Wang D-P, Jiang F-Y, Zeng X-Y, et al. Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors. Genes & Diseases, 2023, 10(2): 389-392. https://doi.org/10.1016/j.gendis.2022.07.001